Department of Cellular Pathology, West Suffolk Hospital, Bury St Edmunds, Suffolk, UK.
Virchows Arch. 2013 Nov;463(5):633-6. doi: 10.1007/s00428-013-1477-2. Epub 2013 Aug 28.
The aim of this 4-year audit was to establish whether sessile serrated polyps/adenomas (SSP/A) were diagnosed in a district general hospital in the UK. The study also explored whether SSP/A in the right colon were misdiagnosed as hyperplastic polyps. A retrospective search of the computer records from 2009 to 2012 inclusive for all lesions diagnosed and coded as SSP/A and/or hyperplastic polyps proximal to the splenic flexure was undertaken. All slides were reviewed and a diagnosis of SSP/A made using the criteria recently suggested by the American College of Gastroenterology. Over the study period, no cases of SSP/A were made. On review of all hyperplastic polyps proximal to the splenic flexure, 13/31 in 2009, 17/40 in 2010, 19/48 in 2011 and 16/48 in 2012 were re-classified as SSP/A. The most likely reason for the under-diagnosis of SSP/A is lack of awareness of the lesion both clinically and by pathologists. Adequate biopsies and deeper sections are important to help make the diagnosis of SSP/A. This study shows that SSP/A are reasonably frequently encountered in non-specialist practice settings and that both clinicians and pathologist in this setting need to be aware of its existence.
本为期 4 年的审计旨在确定英国一家地区综合医院是否诊断出了无蒂锯齿状息肉/腺瘤（SSP/A）。该研究还探讨了右半结肠的 SSP/A 是否被误诊为增生性息肉。对 2009 年至 2012 年 inclusive 期间所有被诊断为 SSP/A 和/或增生性息肉且位于脾曲近端的计算机记录进行了回顾性搜索。所有幻灯片均进行了审查，并根据美国胃肠病学院最近提出的标准做出了 SSP/A 的诊断。在研究期间，未发现 SSP/A 病例。对脾曲近端所有增生性息肉进行回顾性检查后，2009 年的 31 例中有 13 例、2010 年的 40 例中有 17 例、2011 年的 48 例中有 19 例、2012 年的 48 例中有 16 例被重新归类为 SSP/A。SSP/A 漏诊的最可能原因是临床和病理医生对病变缺乏认识。充分的活检和更深的切片对于帮助诊断 SSP/A 很重要。本研究表明，SSP/A 在非专科实践环境中相当常见，该环境中的临床医生和病理医生都需要意识到其存在。
