亚历山大病的神经影像学表现。

Neuroimaging findings in Alexander's disease.

作者信息

Bobele G B, Garnica A, Schaefer G B, Leonard J C, Wilson D, Marks W A, Leech R W, Brumback R A

机构信息

Department of Neurology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City 73126.

出版信息

J Child Neurol. 1990 Jul;5(3):253-8. doi: 10.1177/088307389000500321.

DOI:10.1177/088307389000500321

PMID:2398241

Abstract

We present the findings from magnetic resonance imaging, computed tomographic scan, and single photon emission computed tomography of the brain in a 2-year-old girl with Alexander's disease. Computed tomographic scans showed prominent low-density white matter throughout the cerebral hemispheres. Magnetic resonance imaging showed increased T2 signal from the cerebral white matter but not the cerebellum or brain stem. Single photon emission computed tomography revealed diminished cerebral metabolism, particularly in the frontal regions, as compared with the cerebellum.

摘要

我们展示了一名患有亚历山大病的2岁女孩脑部的磁共振成像、计算机断层扫描和单光子发射计算机断层扫描的结果。计算机断层扫描显示整个大脑半球有明显的低密度白质。磁共振成像显示大脑白质T2信号增强，但小脑和脑干未增强。与小脑相比，单光子发射计算机断层扫描显示大脑代谢降低，尤其是额叶区域。