博茨瓦纳生长发育迟缓儿童中结核病和艾滋病筛查的效果。
Yield of screening for TB and HIV among children failing to thrive in Botswana.
机构信息
Botswana-UPenn Partnership, Gaborone, Botswana.
出版信息
J Trop Pediatr. 2014 Feb;60(1):27-32. doi: 10.1093/tropej/fmt072. Epub 2013 Aug 27.
Abstract
BACKGROUND
Failure to thrive (FTT) is a sign of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. We assessed TB and HIV prevalence in children with FTT at one clinic in Botswana.
METHODS
In July 2010, we screened all children attending a 'Well Child' clinic for FTT. Children with FTT were referred to a paediatrician who: (i) assessed causes of FTT, (ii) evaluated for HIV and TB and (iii) reviewed the patient chart for evaluations for TB and HIV.
RESULTS
Of 919 children screened, 176 (19%) had FTT. One hundred eighteen (67%) children saw a paediatrician, and of these, 95 (81%) completed the TB evaluation. TB was newly diagnosed in 6 of 95 (6%). At review, HIV status was known in 23 of 118 (19%). Ninety-five had an unknown HIV status. Forty-five (47%) tested for HIV; all tested HIV-negative.
CONCLUSION
TB and HIV screening among children with FTT diagnosed TB in 6% of cases completing an evaluation, but no new HIV infections.
摘要
背景
发育不良（FTT）是结核病（TB）和人类免疫缺陷病毒（HIV）感染的迹象。我们评估了博茨瓦纳一家诊所中患有 FTT 的儿童的 TB 和 HIV 患病率。
方法
2010 年 7 月，我们对所有参加“健康儿童”诊所的儿童进行了 FTT 筛查。患有 FTT 的儿童被转介给儿科医生，儿科医生：（i）评估 FTT 的原因，（ii）评估 HIV 和 TB，以及（iii）审查患者的 TB 和 HIV 评估图表。
结果
在筛查的 919 名儿童中，有 176 名（19%）患有 FTT。有 118 名（67%）儿童看了儿科医生，其中 95 名（81%）完成了 TB 评估。在这 95 名儿童中，有 6 名（6%）新诊断为 TB。在复查时，已知 23 名（19%）儿童的 HIV 状况。有 118 名儿童 HIV 状况未知。有 45 名（47%）接受了 HIV 检测；所有检测均为 HIV 阴性。
结论
对患有 FTT 的儿童进行 TB 和 HIV 筛查，在完成评估的儿童中发现了 6%的 TB 病例，但没有新的 HIV 感染。
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