Espie C A, Gillies J B, Montgomery J M
Ravenspark Hospital, Irvine, Ayrshire, Scotland.
J Ment Defic Res. 1990 Aug;34 ( Pt 4):351-60. doi: 10.1111/j.1365-2788.1990.tb01545.x.
The relationship between psychosocial behaviour, antiepileptic regime (polytherapy compared to monotherapy) and seizure frequency was explored in a sample of mentally handicapped adults living in the community. Locus of control perceptions were studied in relation to seizure frequency. Antiepileptic polypharmacy was found to have a detrimental effect upon psychosocial functioning independent of seizure frequency, which is itself a risk factor for social disturbance; and external perceptions of locus of control predominated. The distribution of drugs used is reported. These results are discussed in the context of implications for future research in the areas of coping, mental handicap and antiepileptic pharmacotherapy.
在一组居住在社区的成年智障人士样本中，探讨了心理社会行为、抗癫痫治疗方案（联合治疗与单一治疗相比）与癫痫发作频率之间的关系。研究了控制源认知与癫痫发作频率的关系。发现抗癫痫药物联合使用对心理社会功能有不利影响，且独立于癫痫发作频率，而癫痫发作频率本身就是社会干扰的一个风险因素；并且控制源的外部认知占主导。报告了所用药物的分布情况。在应对、智力障碍和抗癫痫药物治疗领域对未来研究的影响背景下讨论了这些结果。
