Barwing Jürgen, Pedroni Cristina, Olgemöller Ulrike, Quintel Michael, Moerer Onnen
Crit Care. 2013 Aug 28;17(4):R182. doi: 10.1186/cc12865.
A reliable prediction of successful weaning from respiratory support may be crucial for the overall outcome of the critically ill patient. The electrical activity of the diaphragm (EAdi) allows one to monitor the patients' respiratory drive and their ability to meet the increased respiratory demand. In this pilot study, we compared the EAdi with conventional parameters of weaning failure, such as the ratio of respiratory rate to tidal volume.
We studied 18 mechanically ventilated patients considered difficult to wean. For a spontaneous breathing trial (SBT), the patients were disconnected from the ventilator and given oxygen through a T-piece. The SBT was evaluated by using standard criteria.
Twelve patients completed the SBT successfully, and six failed. The EAdi was significantly different in the two groups. We found an early increase in EAdi in the failing patients that was more pronounced than in any of the patients who successfully passed the SBT. Changes in EAdi predicted an SBT failure earlier than did conventional parameters.
EAdi monitoring adds valuable information during weaning from the ventilator and may help to identify patients who are not ready for discontinuation of respiratory support.
对于危重症患者的总体预后而言,可靠地预测呼吸支持的成功撤机可能至关重要。膈肌电活动(EAdi)能够用于监测患者的呼吸驱动力及其满足增加的呼吸需求的能力。在这项前瞻性研究中,我们将EAdi与撤机失败的传统参数(如呼吸频率与潮气量之比)进行了比较。
我们研究了18例被认为难以撤机的机械通气患者。对于自主呼吸试验(SBT),将患者与呼吸机断开连接,并通过T形管给予氧气。采用标准标准对SBT进行评估。
12例患者成功完成SBT,6例失败。两组患者的EAdi存在显著差异。我们发现失败患者的EAdi早期升高比任何成功通过SBT的患者更为明显。EAdi的变化比传统参数更早地预测SBT失败。
EAdi监测在呼吸机撤机过程中增加了有价值的信息,并可能有助于识别尚未准备好停止呼吸支持的患者。