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[食管癌的分子生物学综述]

[Molecular biological review of esophageal cancer].

作者信息

Yokobori Takehiko, Kuwano Hiroyuki

机构信息

Department of General Surgical Science, Gunma University, Maebashi, Japan.

出版信息

Kyobu Geka. 2013 Jan;66(1):73-84.

Abstract

Esophageal squamous cell carcinoma accounts for most esophageal cancers in East Asia. Esophageal adenocarcinoma arises from Barrett's esophagus. However, patients with advanced disease remain poor prognosis. Therefore, it is needed to clarify the carcinogenic mechanism and cancer metastatic process in esophageal cancer. Here, we described the recent research approaches of microarray and next generation sequence in esophageal squamous cell carcinoma and esophageal adenocarcinoma.

摘要

食管鳞状细胞癌占东亚地区大多数食管癌病例。食管腺癌起源于巴雷特食管。然而,晚期疾病患者的预后仍然很差。因此,有必要阐明食管癌的致癌机制和癌症转移过程。在此,我们描述了食管鳞状细胞癌和食管腺癌中微阵列和下一代测序的最新研究方法。

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