Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond.
作者信息
Ciorba Matthew A
机构信息
Division of Gastroenterology, Inflammatory Bowel Diseases Program, Washington University in St Louis, St Louis, MO.
出版信息
Am J Clin Nutr. 2013 Oct;98(4):863-4. doi: 10.3945/ajcn.113.072025. Epub 2013 Aug 28.
Abstract
摘要
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本文引用的文献
1
Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 status.血浆中犬尿氨酸途径中酶的底物产物比作为功能性维生素 B-6 状态的指标。
Am J Clin Nutr. 2013 Oct;98(4):934-40. doi: 10.3945/ajcn.113.064998. Epub 2013 Sep 4.
2
A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolites.色氨酸通过犬尿氨酸途径代谢的数学模型为维生素 B-6 缺乏、色氨酸负荷和诱导色氨酸 2,3-双加氧酶对色氨酸代谢物的影响提供了深入了解。
J Nutr. 2013 Sep;143(9):1509-19. doi: 10.3945/jn.113.174599. Epub 2013 Jul 31.
3
Urinary excretion of kynurenine and tryptophan, cardiovascular events, and mortality after elective coronary angiography.色氨酸和犬尿氨酸尿液排泄与择期冠状动脉造影后的心血管事件和死亡率。
Eur Heart J. 2013 Sep;34(34):2689-96. doi: 10.1093/eurheartj/eht264. Epub 2013 Jul 25.
4
IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.IDO1 代谢物激活 β-连环蛋白信号通路，促进小鼠癌细胞增殖和结肠肿瘤发生。
Gastroenterology. 2013 Aug;145(2):416-25.e1-4. doi: 10.1053/j.gastro.2013.05.002. Epub 2013 May 10.
5
Indoleamine 2,3 dioxygenase in intestinal disease.肠病中的吲哚胺 2,3-双加氧酶。
Curr Opin Gastroenterol. 2013 Mar;29(2):146-52. doi: 10.1097/MOG.0b013e32835c9cb3.
6
Kynurenines in the mammalian brain: when physiology meets pathology.哺乳动物大脑中的犬尿氨酸：当生理学遇到病理学。
Nat Rev Neurosci. 2012 Jul;13(7):465-77. doi: 10.1038/nrn3257.
7
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.一种人类芳香烃受体的内源性肿瘤促进配体。
Nature. 2011 Oct 5;478(7368):197-203. doi: 10.1038/nature10491.
8
Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity.色氨酸分解代谢途径的血清分析：与克罗恩病活动的相关性。
Inflamm Bowel Dis. 2012 Jul;18(7):1214-20. doi: 10.1002/ibd.21849. Epub 2011 Aug 5.
9
Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation.低血浆维生素 B-6 水平通过色氨酸通路影响伴有全身炎症的心血管病患者的代谢。
J Nutr. 2011 Apr 1;141(4):611-7. doi: 10.3945/jn.110.133082. Epub 2011 Feb 10.
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Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial.冠状动脉造影术后接受降低同型半胱氨酸的B族维生素治疗的患者的死亡率和心血管事件：一项随机对照试验。
JAMA. 2008 Aug 20;300(7):795-804. doi: 10.1001/jama.300.7.795.
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