Andersen Poul Erik, Kjeldsen Anette D
Department of Radiology (PEA).
Acta Radiol Short Rep. 2012 Mar 29;1(2). doi: 10.1258/arsr.2012.120001. eCollection 2012.
Pulmonary arteriovenous malformations (PAVMs) with feeding arteries of 3 mm or more have been shown to be associated with paradoxical embolization and serious neurologic complications. Therefore it is generally recommended to occlude feeding arteries of this size, while smaller feeding arteries often are left untreated. However, neurologic complications have also been described in patients with small PAVMs, and it has not been possible to stratify risk by size of feeding artery and thus there is no evidence that 3 mm is the critical size of the feeding artery potentially giving complications. Further, it is well-known that with time PAVMs and their feeding arteries may enlarge. Also, embolization of small feeding arteries will minimize the risk of paradoxical emboli and reduce the need for CT follow-up controls in these patients. Two cases demonstrate the possibility to embolize small feeding arteries.
已证实,供血动脉直径达3毫米或以上的肺动静脉畸形(PAVM)与反常栓塞及严重神经并发症相关。因此,一般建议封堵这种大小的供血动脉,而较小的供血动脉通常不予治疗。然而,小型PAVM患者也有神经并发症的报道,且无法根据供血动脉大小对风险进行分层,因此没有证据表明3毫米是可能引发并发症的供血动脉临界大小。此外,众所周知,随着时间推移,PAVM及其供血动脉可能会增大。而且,栓塞小型供血动脉将使反常栓塞的风险降至最低,并减少这些患者进行CT随访检查的必要性。两例病例证明了栓塞小型供血动脉的可能性。