Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650500, PR China.
Carbohydr Polym. 2013 Oct 15;98(1):861-9. doi: 10.1016/j.carbpol.2013.07.010. Epub 2013 Jul 12.
The inclusion complexation behavior, characterization and binding ability of naringenin with β-cyclodextrin and its derivatives were investigated in both solution and the solid state by means of XRD, DSC, SEM, (1)H and 2D NMR and UV-vis spectroscopy. The results showed that the water solubility and thermal stability of naringenin were obviously increased in the inclusion complex with cyclodextrins. This satisfactory water solubility and high thermal stability of the naringenin/CD complexes will be potentially useful for their application as herbal medicines or healthcare products.
通过 X 射线衍射（XRD）、差示扫描量热法（DSC）、扫描电子显微镜（SEM）、氢核磁共振（1H NMR）和二维核磁共振（2D NMR）以及紫外-可见光谱法，研究了柚皮素与β-环糊精及其衍生物在溶液和固态中的包合络合行为、特性和结合能力。结果表明，在与环糊精的包合络合物中，柚皮素的水溶性和热稳定性明显提高。柚皮素/CD 配合物具有令人满意的水溶性和高热稳定性，这将使其有可能作为草药药物或保健品得到应用。
