Department of Clinical Sciences/Ophthalmology (Behndig), Umeå University Hospital, Umeå, Sweden.
J Cataract Refract Surg. 2013 Sep;39(9):1421-31. doi: 10.1016/j.jcrs.2013.06.014.
Data on practice patterns for prophylaxis against infectious postoperative endophthalmitis (IPOE) during cataract surgery in 9 European countries were searched in national registers and reviews of published surveys. Summary reports assessed each nation's IPOE rates, nonantibiotic prophylactic routines, topical and intracameral antibiotic use, and coherence to the European Society of Cataract & Refractive Surgeons (ESCRS) 2007 guidelines. Although the reliability and completeness of available data vary between countries, the results show that IPOE rates differ significantly. Asepsis routines with povidone-iodine and postoperative topical antibiotics are generally adopted. Use of preoperative and perioperative topical antibiotics as well as intracameral cefuroxime varies widely between and within countries. Five years after publication of the ESCRS guidelines, there is no consensus on intracameral cefuroxime use. Major obstacles include legal barriers or persisting controversy about the scientific rationale for systematic intracameral cefuroxime use in some countries and, until recently, lack of a commercially available preparation.
在 9 个欧洲国家的国家登记处和已发表调查的综述中，检索了关于白内障手术中预防感染性术后眼内炎（IPOE）的实践模式的数据。总结报告评估了每个国家的 IPOE 发生率、非抗生素预防方案、局部和眼内抗生素使用情况，以及与欧洲白内障和屈光外科医师学会（ESCRS）2007 年指南的一致性。尽管各国之间现有数据的可靠性和完整性存在差异，但结果表明 IPOE 发生率差异显著。普遍采用聚维酮碘消毒和术后局部使用抗生素的无菌操作规程。术前和围手术期局部使用抗生素以及眼内注射头孢呋辛在国家之间和国家内部差异很大。ESCRS 指南发布 5 年后，对于眼内注射头孢呋辛的使用仍未达成共识。主要障碍包括一些国家在法律上存在障碍或对系统性眼内注射头孢呋辛使用的科学依据存在争议，以及直到最近缺乏可商业获得的制剂。
