Sorhus Meg D, Corr Amanda, Sun Xiaocun, Ward Daniel A
Department of Small Animal Clinical Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, Tennessee, United States of America.
Office of Information Technology, University of Tennessee, Knoxville, TN, USA.
PeerJ. 2021 Oct 22;9:e12305. doi: 10.7717/peerj.12305. eCollection 2021.
To assess the effectiveness of postoperative administration of oral antibiotics at reducing the incidence of endophthalmitis following phacoemulsification cataract extraction in dogs.
Medical records of the University of Tennessee College of Veterinary Medicine were reviewed for cases having undergone phacoemulsification and divided according to whether or not they had received oral antibiotics postoperatively. Records were then evaluated for a diagnosis of endophthalmitis and incidence rates between the group receiving postoperative oral antibiotics and the group not receiving postoperative oral antibiotics were compared.
A total of 215 patients (368 eyes) were identified by the search. One-hundred twelve patients (197 eyes) were treated with oral antibiotics postoperatively. One-hundred and three patients (171 eyes) were not treated with oral antibiotics postoperatively. Three cases of endophthalmitis were identified, with one in the antibiotic-treated group and two in the non-antibiotic treated group ( > 0.05, Fisher's exact test).
The overall incidence of endophthalmitis at the University of Tennessee from 1997-2010 was 0.82%. The rate of post-phacoemulsification endophthalmitis was unaffected by the postoperative administration of oral antibiotics.
评估犬白内障超声乳化摘除术后口服抗生素给药在降低眼内炎发生率方面的有效性。
回顾田纳西大学兽医学院的病历，筛选出接受超声乳化手术的病例，并根据术后是否接受口服抗生素进行分组。然后对病历进行评估以诊断眼内炎，并比较接受术后口服抗生素组和未接受术后口服抗生素组的发生率。
通过检索共识别出215例患者（368只眼）。其中112例患者（197只眼）术后接受了口服抗生素治疗。103例患者（171只眼）术后未接受口服抗生素治疗。共识别出3例眼内炎病例，抗生素治疗组1例，非抗生素治疗组2例（Fisher精确检验，P>0.05）。
1997年至2010年田纳西大学眼内炎的总体发生率为0.82%。白内障超声乳化术后眼内炎的发生率不受术后口服抗生素给药的影响。
