Department of Cardiovascular Surgery, University Medical Center Ljubljana, Ljubljana, Slovenia.
Silesian Center For Heart Diseases, Zabrze, Poland.
J Thorac Cardiovasc Surg. 2014 Apr;147(4):1411-6. doi: 10.1016/j.jtcvs.2013.06.057. Epub 2013 Aug 26.
The objective of this collaborative, multicenter, European effort was to evaluate the outcomes of the convergent procedure for the treatment of persistent and long-standing persistent atrial fibrillation (AF) in consecutive patients at 4 European centers.
Outcomes of consecutive patients, undergoing the convergent procedure at 4 European centers, were evaluated in this study. Epicardial ablation was performed before endocardial ablation. Convergent procedure outcomes were recorded by interrogation of implanted loop recorders or Holter monitors. Rhythm status and required interventions (antiarrhythmic drugs, cardioversions, and repeat ablations) were quantified 6 and 12 months after the procedure. Outcomes, monitoring type, and patient baseline characteristics were analyzed and reported.
Seventy-three consecutive patients presenting with persistent AF (30.1%) or long-standing persistent AF (69.9%) underwent the convergent procedure between January 2010 and December 2011. At 6 months, 82% (56/68) were in sinus rhythm. At 12 months, 80% (53/66) were in sinus rhythm; single-procedure maintenance of sinus rhythm without postblanking period interventions was 76% (50/66); 52% (34/66) were in sinus rhythm and not receiving antiarrhythmic drugs.
This multicenter European collaborative effort demonstrated that the convergent procedure is a safe and efficacious treatment option for persistent and long-standing persistent AF.
本项协作性、多中心、欧洲努力的目的是评估在 4 个欧洲中心连续患者中应用汇聚程序治疗持续性和长期持续性心房颤动(AF)的结果。
本研究评估了在 4 个欧洲中心接受汇聚程序治疗的连续患者的结果。在进行心内膜消融之前进行心外膜消融。通过植入式环路记录器或动态心电图监测仪来记录汇聚程序的结果。在术后 6 个月和 12 个月时,量化节律状态和所需的干预措施(抗心律失常药物、电复律和重复消融)。分析并报告了结果、监测类型和患者基线特征。
2010 年 1 月至 2011 年 12 月期间,73 例持续性 AF(30.1%)或长期持续性 AF(69.9%)的连续患者接受了汇聚程序治疗。术后 6 个月,82%(56/68)患者窦性节律;术后 12 个月,80%(53/66)患者窦性节律;无空白期干预的单次程序维持窦性节律率为 76%(50/66);52%(34/66)患者窦性节律且未服用抗心律失常药物。
这项多中心欧洲合作研究表明,汇聚程序是治疗持续性和长期持续性心房颤动的一种安全有效的治疗选择。