Department of Pediatric Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Cardiothoracic Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
Department of Pediatric Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
J Thorac Cardiovasc Surg. 2014 May;147(5):1568-72. doi: 10.1016/j.jtcvs.2013.07.013. Epub 2013 Aug 26.
Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency.
All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation.
Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days.
The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.
在单心室患者中,心外管道被广泛用于完成 Fontan 循环。尽管聚四氟乙烯管道已被证明具有良好的长期通畅性,但 Dacron(聚对苯二甲酸乙二醇酯)假体的应用仍然很少,目前尚无关于其长期通畅性的信息。
回顾性研究了所有接受心外 Dacron 管道的患者(n=12)。所有受者的初始管道尺寸均为 16mm。Fontan 完成时的平均年龄为 3.1±0.7 岁。有临床症状和/或明显管道狭窄(>50%直径)的患者进行了再次手术。
12 例患者中有 8 例(75%)在 Fontan 手术后平均 6.5±1.8 年时进行了再次手术。所有管道均被 18mm 聚四氟乙烯移植物替换。标本的内表面有广泛的组织沉积物,残留内径为 8-11mm。所有患者均在体外管道置换后存活。除 1 例患者经历长时间胸腔积液引流外,恢复过程均无并发症。平均住院时间为 10.6±12.0 天。
心外 Dacron 管道在全腔静脉肺动脉连接患者中的狭窄发生率较高。这些数据表明,应避免使用这种类型的管道。对于接受 Dacron 心外管道 Fontan 完成的患者,应进行密切随访。