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体外循环 Fontan 手术中涤纶套狭窄发生率高。

High incidence of Dacron conduit stenosis for extracardiac Fontan procedure.

机构信息

Department of Pediatric Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Cardiothoracic Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

Department of Pediatric Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

J Thorac Cardiovasc Surg. 2014 May;147(5):1568-72. doi: 10.1016/j.jtcvs.2013.07.013. Epub 2013 Aug 26.

Abstract

OBJECTIVES

Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency.

METHODS

All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation.

RESULTS

Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days.

CONCLUSIONS

The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.

摘要

目的

在单心室患者中,心外管道被广泛用于完成 Fontan 循环。尽管聚四氟乙烯管道已被证明具有良好的长期通畅性,但 Dacron(聚对苯二甲酸乙二醇酯)假体的应用仍然很少,目前尚无关于其长期通畅性的信息。

方法

回顾性研究了所有接受心外 Dacron 管道的患者(n=12)。所有受者的初始管道尺寸均为 16mm。Fontan 完成时的平均年龄为 3.1±0.7 岁。有临床症状和/或明显管道狭窄(>50%直径)的患者进行了再次手术。

结果

12 例患者中有 8 例(75%)在 Fontan 手术后平均 6.5±1.8 年时进行了再次手术。所有管道均被 18mm 聚四氟乙烯移植物替换。标本的内表面有广泛的组织沉积物,残留内径为 8-11mm。所有患者均在体外管道置换后存活。除 1 例患者经历长时间胸腔积液引流外,恢复过程均无并发症。平均住院时间为 10.6±12.0 天。

结论

心外 Dacron 管道在全腔静脉肺动脉连接患者中的狭窄发生率较高。这些数据表明,应避免使用这种类型的管道。对于接受 Dacron 心外管道 Fontan 完成的患者,应进行密切随访。

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