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心外管道Fontan手术后Gore-Tex移植物状态的中期随访

Midterm follow-up of the status of Gore-Tex graft after extracardiac conduit Fontan procedure.

作者信息

Lee Cheul, Lee Chang-Ha, Hwang Seong Wook, Lim Hong Gook, Kim Soo-Jin, Lee Jae Young, Shim Woo-Sup, Kim Woong-Han

机构信息

Department of Thoracic and Cardiovascular Surgery, Sejong Heart Institute, Sejong General Hospital, 91-121 Sosa Bon 2-dong, Sosa-ku, Bucheon-shi, Kyungki-do 422-232, South Korea.

出版信息

Eur J Cardiothorac Surg. 2007 Jun;31(6):1008-12. doi: 10.1016/j.ejcts.2007.03.013. Epub 2007 Apr 6.

Abstract

OBJECTIVE

Extracardiac conduit Fontan procedure has some theoretical advantages over other types of Fontan procedures, such as optimized flow dynamics, a lower frequency of arrhythmias, and technical ease of procedure. However, lack of growth potential and thrombogenicity of the artificial conduit is the main concern and can possibly lead to reoperation for the conduit stenosis. In this study, we investigated the change and the status of the Gore-Tex graft used in extracardiac conduit Fontan procedure.

METHODS

Between 1996 and 2005, 154 patients underwent extracardiac conduit Fontan procedure using Gore-Tex graft. Among these, 46 patients underwent cardiac catheterization during follow-up period. We measured the internal diameter of the conduit and inferior vena cava angiographically.

RESULTS

Mean follow-up duration was 36.1+/-19.7 months. The conduit diameter used was 16 mm in 10 patients, 18 mm in 16, 20 mm in 14, 22 mm in 4, and 24 mm in 2 patients. The mean conduit-to-inferior vena cava cross-sectional area ratio was 1.25+/-0.33. According to the conduit size used, this ratio was 1.03+/-0.17 for 16 mm conduits, 1.33+/-0.37 for 18 mm, 1.33+/-0.36 for 20 mm, 1.28+/-0.26 for 22 mm, and 1.05+/-0.06 for 24 mm conduits (p<0.05, 16 mm vs 18 mm and 20 mm). The mean percent decrease of the conduit cross-sectional area was 14.3+/-8.5%, and this did not differ significantly according to the conduit size (p=0.82). Follow-up duration and the percent decrease of the conduit cross-sectional area did not show significant correlation (r=0.22, p=0.14). There was no reoperation due to conduit stenosis.

CONCLUSIONS

During midterm follow-up of about 3 years, the conduit cross-sectional area decreased by 14%, and this did not differ according to the conduit size used. The extent of decrease of the conduit cross-sectional area remained stable irrespective of the follow-up duration. Sixteen millimeters conduit showed no evidence of clinically significant stenosis, but careful follow-up is warranted because of the possible conduit stenosis relative to the patients' somatic growth.

摘要

目的

心外管道Fontan手术相较于其他类型的Fontan手术具有一些理论优势,如优化的血流动力学、较低的心律失常发生率以及手术技术简便。然而,人工管道缺乏生长潜力和血栓形成倾向是主要问题,可能导致因管道狭窄而再次手术。在本研究中,我们调查了心外管道Fontan手术中使用的Gore-Tex移植物的变化及状况。

方法

1996年至2005年间,154例患者接受了使用Gore-Tex移植物的心外管道Fontan手术。其中,46例患者在随访期间接受了心导管检查。我们通过血管造影测量了管道内径和下腔静脉内径。

结果

平均随访时间为36.1±19.7个月。使用的管道直径为16mm的有10例患者,18mm的有16例,20mm的有14例,22mm的有4例,24mm的有2例。管道与下腔静脉横截面积的平均比值为1.25±0.33。根据使用的管道尺寸,16mm管道的该比值为1.03±0.17,18mm管道为1.33±0.37,20mm管道为1.33±0.36,22mm管道为1.28±0.26,24mm管道为1.05±0.06(p<0.05,16mm与18mm和20mm相比)。管道横截面积的平均减小百分比为14.3±8.5%,且根据管道尺寸无显著差异(p=0.82)。随访时间与管道横截面积减小百分比无显著相关性(r=0.22,p=0.14)。没有因管道狭窄而再次手术的情况。

结论

在约3年的中期随访中,管道横截面积减小了14%,且根据使用的管道尺寸无差异。无论随访时间长短,管道横截面积的减小程度保持稳定。16mm的管道未显示出临床显著狭窄的证据,但鉴于相对于患者身体生长可能出现的管道狭窄,仍需仔细随访。

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