Dermatology Department, Melanoma Unit, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.
Dermatology. 2013;227(1):62-6. doi: 10.1159/000351715. Epub 2013 Aug 24.
Inverted follicular keratosis (IFK) is a rare benign tumor which usually appears as a firm papule on the face. The diagnosis is generally made by histopathology because the clinical appearance is difficult to differentiate from other lesions. Dermoscopic features of IFK have not been established to date. Herein we describe the dermoscopic findings of 4 cases of IFK. Radial peripheral hairpin vessels surrounded by a whitish halo arranged around a central white-yellowish amorphous area were observed in 3 cases, and glomerular vessels were present in the central area of one of them. The fourth case also presented a central white amorphous area but showed arborizing vessels. Reflectance confocal microscopy (available in 1 case) revealed a broadened honeycomb pattern, epidermal projections and hairpin and glomerular vessels. To our knowledge this is the first case series describing the dermoscopic features of inverted follicular keratosis and the first confocal microscopy description of this entity.
倒置性毛囊角化病（IFK）是一种罕见的良性肿瘤，通常表现为面部坚实的丘疹。由于临床表现难以与其他病变区分，通常通过组织病理学诊断。IFK 的皮肤镜特征尚未确定。本文描述了 4 例 IFK 的皮肤镜表现。3 例观察到呈放射状排列的发夹状血管，周围环绕着白色晕环，围绕着中央的白色-黄白色无定形区域，其中 1 例中央区可见肾小球状血管。第 4 例也表现为中央白色无定形区域，但显示出树枝状血管。反射共聚焦显微镜（1 例可用）显示出宽阔的蜂窝状模式、表皮突起、发夹状和肾小球状血管。据我们所知，这是首例描述倒置性毛囊角化病皮肤镜特征的病例系列，也是首例对该疾病进行共聚焦显微镜描述的病例。
