Pössel Patrick, Mitchell Amanda M, Ronkainen Kimmo, Kaplan George A, Kauhanen Jussi, Valtonen Maarit
University of Louisville, USA
University of Louisville, USA.
J Health Psychol. 2015 Jan;20(1):60-8. doi: 10.1177/1359105313498109. Epub 2013 Aug 29.
Depression and hopelessness predict myocardial infarction, but it is unclear whether depression and hopelessness are independent predictors of myocardial infarction incidents. Hopelessness, depression, and myocardial infarction incidence rate 18 years later were measured in 2005 men. Cox regressions were conducted with hopelessness and depression serving as individual predictors of myocardial infarction. Another Cox model examined whether the two predictors predict myocardial infarction when adjusting for each other. Depression and hopelessness predicted myocardial infarction in independent regressions, but when adjusting for each other, hopelessness, but not depression, predicted myocardial infarction incidents. Thus, these results suggest that depression and hopelessness are not independent predictors of myocardial infarction.
抑郁和绝望可预测心肌梗死，但抑郁和绝望是否为心肌梗死事件的独立预测因素尚不清楚。对2005名男性测量了绝望、抑郁以及18年后的心肌梗死发病率。以绝望和抑郁作为心肌梗死的个体预测因素进行了Cox回归分析。另一个Cox模型检验了在相互调整后这两个预测因素是否能预测心肌梗死。在独立回归分析中，抑郁和绝望可预测心肌梗死，但在相互调整后，只有绝望而非抑郁能预测心肌梗死事件。因此，这些结果表明抑郁和绝望并非心肌梗死的独立预测因素。
