Aronow Mary E, Singh Arun D
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Dev Ophthalmol. 2013;52:85-93. doi: 10.1159/000351062. Epub 2013 Aug 26.
While the primary treatment of eyelid and conjunctival tumors is frequently surgical, several forms of ophthalmic radiation therapy have also been used to treat these malignancies. The goal of radiation therapy is to eradicate tumor burden in a manner that maintains visual function and preserves surrounding sensitive ocular tissues. Ophthalmic radiation may be used as a curative therapy, as adjuvant treatment following surgical excision, or as palliative therapy for advanced cases of eyelid and conjunctival tumors. The following review discusses the indications and outcomes of various modalities of radiation (external beam radiotherapy and brachytherapy) used to treat eyelid tumors (squamous cell carcinoma, basal cell carcinoma, sebaceous gland carcinoma, and melanoma) and conjunctival tumors (squamous cell carcinoma and melanoma).
虽然眼睑和结膜肿瘤的主要治疗方法通常是手术，但也有几种形式的眼科放射治疗被用于治疗这些恶性肿瘤。放射治疗的目标是以维持视觉功能并保留周围敏感眼组织的方式根除肿瘤负荷。眼科放射可作为一种根治性疗法、手术切除后的辅助治疗，或作为眼睑和结膜肿瘤晚期病例的姑息治疗。以下综述讨论了用于治疗眼睑肿瘤（鳞状细胞癌、基底细胞癌、皮脂腺癌和黑色素瘤）和结膜肿瘤（鳞状细胞癌和黑色素瘤）的各种放射治疗方式（外照射放疗和近距离放疗）的适应证和疗效。
