磁共振成像（MRI）与双能X线吸收法（DXA）在测量大腿肌肉大小及与年龄相关的萎缩方面的比较。

Comparison of MRI and DXA to measure muscle size and age-related atrophy in thigh muscles.

作者信息

Maden-Wilkinson T M, Degens H, Jones D A, McPhee J S

机构信息

School of Healthcare Science, Manchester Metropolitan University, John Dalton Building, Oxford Road, Manchester, United Kingdom.

出版信息

J Musculoskelet Neuronal Interact. 2013 Sep;13(3):320-8.

PMID:23989253

Abstract

OBJECTIVES

Magnetic resonance imaging (MRI) and dual-energy x-ray absorptiometry (DXA) were used to examine the thigh lean mass in young and old men and women.

METHODS

A whole-body DXA scan was used to estimate thigh lean mass in young (20 men; 22.4±3.1y; 18 women; 22.1±2.0y) and older adults (25 men; 72.3±4.9y; 28 women; 72.0±4.5y). Thigh lean mass determined with a thigh scan on the DXA or full thigh MRI scans were compared.

RESULTS

Although the thigh lean mass quantified by DXA and MRI in young and older participants were correlated (R(2)=0.88; p<0.001) the magnitude of the differences in thigh lean mass between young and old was smaller with DXA than MRI (old vs. young men 79.5±13.1% and 73.4±11.2%; old vs. young women 88.6±11.8% and 79.4±12.3%, respectively). Detailed analysis of MRI revealed 30% smaller quadriceps muscles in the older than young individuals, while the other thigh muscles were only 18% smaller.

CONCLUSIONS

DXA underestimates the age-related loss of thigh muscle mass in comparison to MRI. The quadriceps muscles were more susceptible to age-related atrophy compared with other thigh muscles.

摘要

目的

使用磁共振成像（MRI）和双能X线吸收法（DXA）检查青年和老年男性及女性的大腿瘦体重。

方法

采用全身DXA扫描评估青年（20名男性，年龄22.4±3.1岁；18名女性，年龄22.1±2.0岁）和老年人（25名男性，年龄72.3±4.9岁；28名女性，年龄72.0±4.5岁）的大腿瘦体重。比较通过DXA大腿扫描或全大腿MRI扫描测定的大腿瘦体重。

结果

尽管青年和老年参与者中通过DXA和MRI量化的大腿瘦体重具有相关性（R² = 0.88；p<0.001），但与MRI相比，DXA显示的青年和老年之间大腿瘦体重差异的幅度较小（老年男性与青年男性分别为79.5±13.1%和73.4±11.2%；老年女性与青年女性分别为88.6±11.8%和79.4±12.3%）。MRI的详细分析显示，老年人的股四头肌比年轻人小30%，而大腿其他肌肉仅小18%。