Department of Nuclear Medicine, Kyungpook National University School of Medicine and Hospital, 807 Hogukno, Buk-gu, Daegu, 702-210, Republic of Korea.
Ann Nucl Med. 2014 Jan;28(1):69-73. doi: 10.1007/s12149-013-0764-y. Epub 2013 Aug 29.
Adrenocortical oncocytoma is a very rare tumor, which is not malignant and nonfunctioning in most cases. We report a case of a 53-year-old male with a 9.8 cm sized hyperfunctioning, well-encapsulated adrenal mass, which exhibited by high FDG uptake on a PET/CT scan. The patient had complained of symptoms of Cushing's syndrome for 4 months. Laparoscopic adrenalectomy was performed and the mass was pathologically confirmed as adrenocortical oncocytoma of uncertain malignant potential. Four years after surgery, the tumor recurred with distant metastases, which was proven by subsequent biopsy. 18F-FDG PET/CT also showed hypermetabolism in the recurred tumor and multiple metastatic lesions. Adrenocortical oncocytoma of borderline malignant potential with high FDG uptake may require long-term follow-up with clinical, hormonal, and imaging evaluations.
肾上腺皮质嗜酸细胞瘤是一种非常罕见的肿瘤，大多数情况下为良性且无功能。我们报告了一例 53 岁男性患者，其患有 9.8 厘米大小的功能性、包膜完整的肾上腺肿块，在 PET/CT 扫描上表现为 FDG 摄取增高。该患者有 4 个月的库欣综合征症状。行腹腔镜肾上腺切除术，肿块的病理结果证实为具有不确定恶性潜能的肾上腺皮质嗜酸细胞瘤。术后 4 年，肿瘤复发并发生远处转移，随后的活检证实了这一点。18F-FDG PET/CT 还显示复发肿瘤和多个转移病灶存在高代谢。具有高 FDG 摄取的交界性恶性潜能的肾上腺皮质嗜酸细胞瘤可能需要进行长期的临床、激素和影像学评估随访。
