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[小儿胃十二指肠炎症患者大肠远端段黏膜的临床免疫形态学特征]

[Clinico-immunomorphological characteristics of the mucosa of the distal segments of the large intestine in children with gastroduodenitis].

作者信息

Kovaleva G A, Kononov A V, Miniaĭlo E K, Shcheglov V G

出版信息

Pediatriia. 1990(5):32-7.

PMID:2399064
Abstract

The clinical, x-ray, endoscopic and morphological studies performed in 156 children afflicted with gastroduodenitis have shown that concomitant lesions of the colon are of paramount importance in the genesis of this illness. The immunomorphological assay is the most informative one in the assessment of the pattern of structural alterations in the colonic mucosa. Examination of 71 colonic biopsy specimens has disclosed that 38 patients had minimal alterations in the mucosa characteristic of colodyskinesias and 22 had the signs of chronic inflammation, which plays an important part in goal-oriented therapy and prediction of the disease under consideration.

摘要

对156例患胃十二指肠炎症的儿童进行的临床、X光、内窥镜及形态学研究表明,结肠的并发损伤在该疾病的发病机制中至关重要。免疫形态学检测在评估结肠黏膜结构改变模式方面信息最为丰富。对71份结肠活检标本的检查发现,38例患者黏膜有符合结肠运动障碍的轻微改变,22例有慢性炎症迹象,这在针对该疾病的定向治疗和病情预测中起着重要作用。

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