Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and.
J Neurosurg. 2013 Nov;119(5):1156-8. doi: 10.3171/2013.7.JNS13623. Epub 2013 Aug 30.
Intrinsic meningiomas of the superior sagittal sinus pose a significant technical challenge, particularly in the posterior two-thirds of the sinus. Resection is curative but frequently is not possible because of the involvement of critical vascular structures. Here, the authors present the case of a 49-year-old woman with a recurrent meningioma located exclusively in the posterior two-thirds of the sagittal sinus. The patient was treated with a margin dose of 12 Gy and a maximum dose of 24 Gy to the length of the tumor, which measured 16 cm. Five years after treatment, the tumor remains stable and the patient is symptom free. This case demonstrates the unique role that stereotactic radiosurgery can play in the management of meningiomas that are surgically unresectable and have no accepted form of treatment. To the authors' knowledge, 16 cm also represents the longest segment of tumor treated using stereotactic radiosurgery.
上矢状窦内固有脑膜瘤是一个重大的技术挑战，特别是在后三分之二窦内。切除是可以治愈的，但由于涉及关键的血管结构，通常无法进行切除。在这里，作者介绍了一位 49 岁的女性患者，她患有复发性脑膜瘤，仅位于矢状窦的后三分之二处。该患者接受了 12 Gy 的边缘剂量和 24 Gy 的最大剂量，肿瘤长度为 16 厘米。治疗后 5 年，肿瘤仍然稳定，患者无症状。这个病例表明，立体定向放射外科在治疗手术无法切除且尚无公认治疗方法的脑膜瘤方面具有独特作用。据作者所知，16 厘米也代表了使用立体定向放射外科治疗的最长肿瘤段。
