Department of Parasitology and Mycology, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris, Université Paris 13, Bobigny, France.
Clin Microbiol Infect. 2014 Feb;20(2):O139-41. doi: 10.1111/1469-0691.12334. Epub 2013 Aug 30.
There are growing concerns about the emergence of resistance of Sarcoptes scabiei to permethrin and other pyrethroid derivatives. Sarcoptes scabiei mites collected from 40 patients visiting two hospitals near Paris, France, were genotypically characterized considering two parts of their voltage-sensitive sodium channel gene. No nucleotide polymorphism resulting in a codon change at codon 733 or other positions associated with knockdown resistance in other arthropods has been identified. These data may establish a reference line for future surveys of the susceptibility of S. scabiei in the area.
人们越来越担心疥螨对氯菊酯和其他拟除虫菊酯衍生物产生抗药性。从法国巴黎附近的两家医院就诊的 40 名患者身上采集的疥螨进行了基因分型特征分析，考虑了其电压敏感钠离子通道基因的两个部分。未发现导致 733 密码子或与其他节肢动物击倒抗性相关的其他位置发生核苷酸多态性的密码子变化。这些数据可能为该地区未来疥螨易感性调查建立参考线。
