Department of Dermatology, Kuwait University Hospital, Sana'a University, Sana'a, Yemen.
J Cosmet Dermatol. 2013 Sep;12(3):170-8. doi: 10.1111/jocd.12052.
Carbon dioxide (CO2 ) and erbium-yttrium aluminum garnet (Er-YAG) lasers are the gold standards in ablative skin resurfacing. Neodymium-doped yttrium aluminum garnet (Nd-YAG) laser is considered a nonablative skin resurfacing laser whose usage is limited due to its high cost.
To assess the efficacy and safety of Nd-YAG as an ablative resurfacing laser and to compare the results with those previously published for CO2 and Erbium-YAG lasers.
PATIENTS/METHODS: A total of 296 patients (251 female and 45 male) with Fitzpatrick skin types III-IV and dermatological conditions amenable to ablative skin resurfacing participated in this study. Nd-YAG laser parameters assessed were wavelength (1064 nm), pulse duration (5 ms), fluence (10 J/cm(2) ), and spot size (8-10 mm). Efficacy of Nd-YAG laser was assessed by comparing pre- and posttreatment photographs.
An improvement of 30-80% was observed in treated patients. The degree of improvement correlated positively with the number of laser sessions. The most common side effect was hyperpigmentation. Other side effects were less common and mild in intensity compared with published results for gold standard ablative lasers.
Not only was the Nd-YAG laser found to be as effective as Er-YAG and CO2 lasers, but treated patients also had shorter recovery and treatment times, and at lower cost.
二氧化碳（CO2）和铒钇铝石榴石（Er-YAG）激光是磨皮术的金标准。掺钕钇铝石榴石（Nd-YAG）激光被认为是一种非剥脱性皮肤重塑激光，由于其成本高，其使用受到限制。
评估 Nd-YAG 作为磨皮术激光的疗效和安全性，并将结果与 CO2 和 Erbium-YAG 激光的先前发表结果进行比较。
患者/方法：共有 296 名（251 名女性和 45 名男性）皮肤类型为 III-IV 型的 Fitzpatrick 患者和适合磨皮术的皮肤状况患者参加了这项研究。评估的 Nd-YAG 激光参数包括波长（1064nm）、脉冲持续时间（5ms）、能量密度（10J/cm²）和光斑大小（8-10mm）。通过比较治疗前后的照片评估 Nd-YAG 激光的疗效。
治疗患者观察到 30-80%的改善。改善程度与激光治疗次数呈正相关。最常见的副作用是色素沉着过度。其他副作用比发表的金标准剥脱性激光的结果更常见且强度更轻。
Nd-YAG 激光不仅与 Er-YAG 和 CO2 激光一样有效，而且治疗患者的恢复和治疗时间更短，成本更低。
