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The cardiovascular safety of diabetes drugs--insights from the rosiglitazone experience.

作者信息

Hiatt William R, Kaul Sanjay, Smith Robert J

机构信息

Division of Cardiology and Colorado Prevention Center Clinical Research, Department of Medicine, University of Colorado School of Medicine, Aurora, USA.

出版信息

N Engl J Med. 2013 Oct 3;369(14):1285-7. doi: 10.1056/NEJMp1309610. Epub 2013 Sep 2.

DOI:10.1056/NEJMp1309610
PMID:23992603
Abstract
摘要

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The cardiovascular safety of diabetes drugs--insights from the rosiglitazone experience.糖尿病药物的心血管安全性——来自罗格列酮经验的见解。
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2
Rosiglitazone: what went wrong?罗格列酮：问题出在哪里？
BMJ. 2010 Sep 6;341:c4848. doi: 10.1136/bmj.c4848.
3
Commentary: What can we learn from the continuing regulatory focus on the thiazolidinediones?评论：我们能从监管机构对噻唑烷二酮类药物持续的关注中学到什么？
BMJ. 2010 Sep 6;341:c4812. doi: 10.1136/bmj.c4812.
4
Rosiglitazone, marketing, and medical science.罗格列酮、市场营销与医学科学。
BMJ. 2010 Apr 7;340:c1848. doi: 10.1136/bmj.c1848.
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The Avandia debate: an unhappy conclusion.文迪雅之争：一个令人不快的结局。
J Diabetes. 2010 Dec;2(4):221-2. doi: 10.1111/j.1753-0407.2010.00096.x.
6
FDA committee urges tight restrictions on rosiglitazone.美国食品药品监督管理局委员会敦促对罗格列酮进行严格限制。
BMJ. 2010 Jul 16;341:c3862. doi: 10.1136/bmj.c3862.
7
Rosiglitazone and cardiovascular risk.罗格列酮与心血管风险。
N Engl J Med. 2007 Jun 14;356(24):2522-4. doi: 10.1056/NEJMe078099. Epub 2007 May 21.
8
The record on rosiglitazone and the risk of myocardial infarction.罗格列酮与心肌梗死风险的记录。
N Engl J Med. 2007 Jul 5;357(1):67-9. doi: 10.1056/NEJMe078116. Epub 2007 Jun 5.
9
Licensing drugs for diabetes.糖尿病药物的许可
BMJ. 2010 Sep 6;341:c4805. doi: 10.1136/bmj.c4805.
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Outlook on diabetes drug less than rosy. Early work suggests that rosiglitazone (Avandia) may not be best for the heart.糖尿病药物前景不乐观。早期研究表明，罗格列酮（文迪雅）可能对心脏并非最佳选择。
Harv Heart Lett. 2007 Aug;17(12):1-2.

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Combined therapeutic strategy based on blocking the deleterious effects of AGEs for accelerating diabetic wound healing.基于阻断晚期糖基化终末产物的有害作用以加速糖尿病伤口愈合的联合治疗策略。
Regen Biomater. 2024 Jun 5;11:rbae062. doi: 10.1093/rb/rbae062. eCollection 2024.
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Rosiglitazone attenuates Acute Kidney Injury from hepatic ischemia-reperfusion in mice by inhibiting arachidonic acid metabolism through the PPAR-γ/NF-κB pathway.罗格列酮通过 PPAR-γ/NF-κB 通路抑制花生四烯酸代谢，减轻小鼠肝缺血再灌注引起的急性肾损伤。
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Cardiorenal syndrome and diabetes: an evil pairing.心肾综合征与糖尿病：一对有害组合。
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