Department of Internal Medicine, VU University Medical Center, Room ZH4A35, PO Box 7057, Amsterdam NL-1007MB, The Netherlands.
Med Clin North Am. 2013 Sep;97(5):911-46. doi: 10.1016/j.mcna.2013.04.005. Epub 2013 Jun 5.
Foot infections are common in persons with diabetes mellitus. Most diabetic foot infections occur in a foot ulcer, which serves as a point of entry for pathogens. Unchecked, infection can spread contiguously to involve underlying tissues, including bone. A diabetic foot infection is often the pivotal event leading to lower extremity amputation, which account for about 60% of all amputations in developed countries. Given the crucial role infections play in the cascade toward amputation, all clinicians who see diabetic patients should have at least a basic understanding of how to diagnose and treat this problem.
足部感染在糖尿病患者中很常见。大多数糖尿病足感染发生在足部溃疡处，这是病原体进入的一个点。如果不加以控制，感染会连续扩散到包括骨骼在内的深层组织。糖尿病足感染通常是导致下肢截肢的关键事件，占发达国家所有截肢的约 60%。鉴于感染在向截肢发展的级联反应中起着至关重要的作用，所有治疗糖尿病患者的临床医生都应该至少对如何诊断和治疗这一问题有一个基本的了解。
