Institute & Hospital of Hepatobiliary Surgery, Key Laboratory of Digital Hepatobiliary Surgery of Chinese PLA, Chinese PLA Medical Academy, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China.
Eur J Surg Oncol. 2013 Nov;39(11):1236-42. doi: 10.1016/j.ejso.2013.08.002. Epub 2013 Aug 29.
Surgical resection in the treatment of hepatocellular carcinoma (HCC) originating in the caudate lobe is challenging because of its deep location in the liver and possibly worse prognosis. We evaluated the overall survival of patients with solitary caudate small HCC who underwent laparoscopic radiofrequency ablation (RFA).
This is a retrospective study on patients who underwent laparoscopic RFA (RFA) for solitary small HCC.
Twenty-seven (27) patients underwent laparoscopic caudate lobe RFA for solitary small HCC. The average tumor size was 2.8 cm. The overall survival rates were 96.3%, 88.9%, 74.1%, 74.1% and 62.9% at 1, 2, 3, 4 and 5 years respectively. The disease-free survival after RFA was 92.6%, 52.9%, 44.4%, 33.3% and 33.3% at 1, 2, 3, 4 and 5 years respectively. Most common postoperative complication was pleural effusion (7/27, 25.9%), and followed by transient hemoglobinuria (2/27, 7.4%).
Laparoscopic RFA for caudate lobe small HCC is a safe and feasible procedure without perioperative mortality. Through a systematic review of other therapeutic options on caudate HCC, its overall outcome is comparable to that of surgical resection.
由于尾状叶位于肝脏深部，手术切除治疗起源于尾状叶的肝细胞癌（HCC）具有挑战性，并且可能预后更差。我们评估了接受腹腔镜射频消融（RFA）治疗的单发尾状叶小 HCC 患者的总生存率。
这是一项对接受腹腔镜 RFA（RFA）治疗单发小 HCC 的患者进行的回顾性研究。
27 例患者因单发小 HCC 行腹腔镜尾状叶 RFA。平均肿瘤大小为 2.8cm。1、2、3、4 和 5 年的总生存率分别为 96.3%、88.9%、74.1%、74.1%和 62.9%。RFA 后无病生存率分别为 1、2、3、4 和 5 年的 92.6%、52.9%、44.4%、33.3%和 33.3%。最常见的术后并发症是胸腔积液（7/27，25.9%），其次是短暂性血红蛋白尿（2/27，7.4%）。
腹腔镜 RFA 治疗尾状叶小 HCC 是一种安全可行的方法，无围手术期死亡率。通过对其他治疗尾状叶 HCC 的治疗方法进行系统评价，其总体结果与手术切除相当。
