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头孢洛林治疗耐甲氧西林金黄色葡萄球菌菌血症:病例系列和文献复习。

Ceftaroline for meticillin-resistant Staphylococcus aureus bacteraemia: case series and review of the literature.

机构信息

Wright State University Boonshoft School of Medicine, Miami Valley Hospital, 128 East Apple Street, Weber CHE 2nd Floor, Dayton, OH 45409, USA.

出版信息

Int J Antimicrob Agents. 2013 Nov;42(5):450-5. doi: 10.1016/j.ijantimicag.2013.07.005. Epub 2013 Aug 11.

Abstract

Data regarding ceftaroline use for meticillin-resistant Staphylococcus aureus bacteraemia (MRSAB) are lacking. Here we review the outcomes of 31 patients with MRSAB treated with ceftaroline, including 9 patients with endocarditis. Clinical success was observed in 23 patients (74.2%). Adverse events associated with prolonged therapy were rare and included eosinophilic pneumonia, rash and diarrhoea. We conclude that ceftaroline can be used for MRSAB.

摘要

关于头孢洛林治疗耐甲氧西林金黄色葡萄球菌菌血症(MRSAB)的数据尚缺乏。在此,我们回顾了 31 例 MRSAB 患者使用头孢洛林的治疗结果,其中包括 9 例心内膜炎患者。23 例患者(74.2%)观察到临床疗效。与延长治疗相关的不良事件罕见,包括嗜酸性肺炎、皮疹和腹泻。我们的结论是,头孢洛林可用于治疗 MRSAB。

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