Strubel D, Kuntzmann F, Kieffer G, Heldt N
Service de Médecine-Interne Gériatrie, Hôpital de la Robertsau, Strasbourg.
Rev Med Interne. 1990 Mar-Apr;11(2):129-32. doi: 10.1016/s0248-8663(05)82214-3.
Progressive multifocal leucoencephalopathy is a white matter infection caused by a papovavirus. Immunocompromised patients are predominantly affected. We report the case of a 74-year old woman with abdominal lymphoma resistant to chemotherapy. The diagnosis was suggested by cerebral CT and NMR images and was confirmed at postmortem pathological examination. The contribution of complementary examinations to the diagnosis is discussed in the light of recently published studies.
进行性多灶性白质脑病是一种由乳头多瘤空泡病毒引起的白质感染。免疫功能低下的患者是主要受累对象。我们报告了一例74岁患有对化疗耐药的腹部淋巴瘤的女性病例。脑CT和核磁共振成像提示了诊断,并在尸检病理检查中得到证实。根据最近发表的研究讨论了辅助检查对诊断的作用。