Sziray Agnes, Károlyi Zsuzsánna
Miskolci Semmelweis Kórház és Egyetemi Oktatókórház Bőrgyógyászati Osztály Miskolc Jókai Mór u. 4. 3525.
Orv Hetil. 2013 Sep 8;154(36):1407-16. doi: 10.1556/OH.2013.29697.
Pregnancy is associated with hormonal, metabolic, immunologic, haemodynamic and vascular changes which produce physiological and pathological cutaneous manifestations. Most skin disorders during pregnancy represent physiological changes. The specific dermatoses of pregnancy are disease entities almost exclusively related to the pregnancy or the postpartum period. Some dermatoses characteristically improve or exacerbate during pregnancy. Dermatoses of pregnancy can potentially be a serious risk to the foetus. Although the foetal outcome is almost always favourable, early diagnosis and prompt treatment are essential. Use of any medication during pregnancy should be carefully considered, and as few medications as possible should be administered. In this review, the authors discuss the various dermatoses of pregnancy in detail, based on novel classification, aetiology and pathogenesis, diagnostic approach, disease course, prognosis, foetal risk and therapy.
妊娠与激素、代谢、免疫、血流动力学及血管变化相关,这些变化会产生生理和病理的皮肤表现。孕期的大多数皮肤疾病代表生理变化。妊娠特异性皮肤病几乎完全是与妊娠或产后期相关的疾病实体。一些皮肤病在孕期有特征性的改善或加重。妊娠皮肤病对胎儿可能构成严重风险。尽管胎儿结局几乎总是良好的,但早期诊断和及时治疗至关重要。孕期使用任何药物都应仔细考虑,且应尽可能少用药。在这篇综述中,作者基于新的分类、病因和发病机制、诊断方法、病程、预后、胎儿风险及治疗,详细讨论了各种妊娠皮肤病。