Ambros-Rudolph C M, Sticherling M
Hautarztpraxis, Mozartgasse 4, 8010, Graz, Österreich.
Hautklinik, Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.
Hautarzt. 2017 Feb;68(2):87-94. doi: 10.1007/s00105-016-3922-z.
The specific dermatoses of pregnancy represent a heterogeneous group of inflammatory skin diseases related to pregnancy and/or the postpartum period. A clinically relevant classification has been well established over the past 10 years and includes pemphigoid gestationis, polymorphic eruption of pregnancy, intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy. The hallmark of all four entities is severe pruritus that is accompanied by characteristic skin changes. While some of these dermatoses are distressing only to the mother because of pruritus, others may be associated with significant fetal risks. Early diagnosis and prompt treatment are therefore essential. In this review, we discuss in detail pemphigoid gestationis, polymorphic and atopic eruptions of pregnancy whereas intrahepatic cholestasis of pregnancy is discussed in a separate article (Kremer A, Ständer S, DOI 10.1007/s00105-016-3923-y ). Furthermore, we present a helpful algorithm for diagnosis and management of pruritus in pregnancy.
妊娠特异性皮肤病是一组与妊娠和/或产后时期相关的炎症性皮肤病。在过去10年中已建立了一种具有临床相关性的分类,包括妊娠类天疱疮、妊娠多形性皮疹、妊娠肝内胆汁淤积症和妊娠特应性皮疹。所有这四种病症的标志是伴有特征性皮肤变化的严重瘙痒。虽然其中一些皮肤病仅因瘙痒而令母亲痛苦,但其他一些可能与重大的胎儿风险相关。因此,早期诊断和及时治疗至关重要。在本综述中,我们详细讨论妊娠类天疱疮、妊娠多形性和特应性皮疹,而妊娠肝内胆汁淤积症将在另一篇文章中讨论(克雷默A,施坦德S,DOI 10.1007/s00105-016-3923-y)。此外,我们提出了一种有助于诊断和管理妊娠瘙痒的算法。