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妊娠瘙痒的评估与管理。

Assessment and management of itchy skin in pregnancy.

机构信息

MBBS (Hons), BMedSc, FRACGP, DCH, PDipDerm, General Practitioner, Tas.

AM, BSc (Hons), MBBS, MPH, FACD, FAFOEM, Consultant Dermatologist and Occupational Physician; Adjunct Clinical Associate Professor, Monash University, Vic; Honorary Associate Professor, The University of Melbourne, Vic; Director, Occupational Dermatology Research and Education Centre, Vic.

出版信息

Aust J Gen Pract. 2021 Dec;50(12):898-903. doi: 10.31128/AJGP-03-21-5900.

Abstract

BACKGROUND

Women with rashes or itchy skin during pregnancy will often present initially to the general practitioner. Knowledge of the specific dermatoses of pregnancy will assist in diagnosis, management and, importantly, facilitation of timely escalation of care of conditions that can potentially affect the fetus.

OBJECTIVE

The aim of this article is to provide a diagnostic framework for approaching a pruritic rash during pregnancy as well as a helpful summary of management of pregnancy-specific dermatoses. It will assist clinicians in the identification of specific dermatoses that pose fetal risks.

DISCUSSION

In addition to considering non-pregnancy specific conditions when approaching pruritus or a pruritic rash in pregnancy, it is important that clinicians also consider pregnancy-specific dermatoses, which have been reclassified into four categories: polymorphic eruption of pregnancy, pemphigoid gestationis, intrahepatic cholestasis of pregnancy (ICP) and atopic eruption of pregnancy. Unlike the other dermatoses, ICP begins with pruritus, and skin changes are secondary. ICP and pemphigoid gestationis are associated with fetal risks such as prematurity and stillbirth.

摘要

背景

妊娠期间出现皮疹或皮肤瘙痒的女性通常最初会就诊于全科医生。了解妊娠特有的皮肤病有助于诊断、管理,重要的是,有助于及时升级可能影响胎儿的疾病的治疗。

目的

本文旨在为妊娠期间瘙痒性皮疹的诊断提供一个框架,并对妊娠特发性皮肤病的治疗进行总结。它将帮助临床医生识别出具有胎儿风险的特定皮肤病。

讨论

在妊娠瘙痒或瘙痒性皮疹时,除了考虑非妊娠特异性疾病外,临床医生还应考虑妊娠特发性皮肤病,这些疾病已重新分类为四大类:妊娠多形疹、疱疹样天疱疮、妊娠肝内胆汁淤积症(ICP)和妊娠特发性皮疹。与其他皮肤病不同,ICP 以瘙痒开始,皮肤改变是次要的。ICP 和疱疹样天疱疮与早产和死胎等胎儿风险相关。

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