Shulutko B I
Vrach Delo. 1990 Jun(6):21-4.
A study is presented of the humoral mechanisms of arterial hypertension, clinical course and morphological changes of the renal tissue as evidenced by kidney biopsy data in 203 patients with mesangial proliferative glomerulonephritis (GN) depending on the presence of arterial hypertension and time of its development. The development of arterial hypertension is caused by genetic factors and is similar to hypertensive disease by its humoral indices. The mechanisms of initiation of arterial hypertension are also similar at the onset and final stage of GN. The morphological reflexion of arterial hypertension is sclerosis of the medullar layer of the kidneys. The hypertensive syndrome in GN should be considered from the viewpoint of its appearance as it determines the course of nephropathy.
本文呈现了一项关于动脉高血压体液机制、肾组织临床病程及形态学变化的研究。该研究依据203例系膜增生性肾小球肾炎（GN）患者的肾脏活检数据，探讨了动脉高血压的存在及其发展时间。动脉高血压的发生由遗传因素引起，其体液指标与高血压病相似。在GN的发病初期和终末期，动脉高血压的起始机制也相似。动脉高血压的形态学表现为肾髓质层硬化。GN中的高血压综合征应从其出现的角度来考虑，因为它决定了肾病的病程。
