Pilipchuk V N
Vrach Delo. 1990 Jun(6):38-40.
The author investigated the frequency and character of side-effects to penicillin, levomycetin, tetracycline in the treatment of 92 patients with different forms of chronic bronchitis. Clinically all side-effects were subdivided in dysbacteriosis, allergic, toxic and mixed. It was established that the high incidence of side-effects furthers allergization of the body and potentiation of bronchial spasm. That is why the employment of antibiotics in these cases is not indicated. The low incidence of side-effect of antibiotics in purulent bronchitis requires their use under thorough medical surveillance.
作者调查了92例不同类型慢性支气管炎患者在使用青霉素、氯霉素、四环素治疗时副作用的发生频率及特征。临床上,所有副作用分为菌群失调、过敏、毒性及混合性。已证实副作用的高发生率会进一步使机体致敏并增强支气管痉挛。因此,在这些病例中不建议使用抗生素。抗生素在化脓性支气管炎中副作用发生率低,在严格医疗监测下可使用。