Schaffer Paula A, Wobeser Bruce, Dennis Michelle M, Duncan Colleen G
Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, 80523-1619, USA.
Can Vet J. 2013 Mar;54(3):262-6.
A retrospective study evaluated the clinical data and histologic features of non-neoplastic dermatologic lesions in skin biopsies from horses, donkeys, and mules submitted over a 10-year period to the Colorado State University Diagnostic Medicine Center and to the University of Saskatchewan Western College of Veterinary Medicine and Prairie Diagnostic Services. A total of 1793 non-neoplastic biopsies were available for analysis. Based on the histologic description and morphologic diagnosis, each submission was classified as inflammatory, or non-neoplastic/non-inflammatory. Results of this study demonstrate that non-neoplastic equine cutaneous biopsies are predominantly inflammatory, but histopathology alone may not be sufficient to definitively identify the underlying etiologies driving inflammatory lesions. Clinical correlation, including breed, age, and distribution of the cutaneous lesion, as well as ancillary tests such as bacterial or fungal culture are required to complete the clinical picture and arrive at the appropriate clinical diagnosis.
一项回顾性研究评估了在10年期间提交给科罗拉多州立大学诊断医学中心、萨斯喀彻温大学西部兽医学院和草原诊断服务中心的马、驴和骡皮肤活检中非肿瘤性皮肤病变的临床数据和组织学特征。共有1793份非肿瘤性活检样本可供分析。根据组织学描述和形态学诊断，每份样本被分类为炎症性或非肿瘤性/非炎症性。这项研究的结果表明，非肿瘤性马皮肤活检主要是炎症性的，但仅靠组织病理学可能不足以明确识别导致炎症性病变的潜在病因。需要临床关联，包括品种、年龄和皮肤病变的分布，以及诸如细菌或真菌培养等辅助检查，以完善临床情况并得出适当的临床诊断。
