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[丙酮酸试验在人群大规模检查中早期发现糖尿病的重要性]

[The importance of the pyruvate test for the early detection of diabetes mellitus in a mass examination of the population].

作者信息

Tomashevskiĭ Ia I, Kravchenko V I, Tomashevskaia N Ia, Sergienko A A, Kho K S, Denega E M, Ershova T A, Kostur Z V, Povch O I, Sadova O M

出版信息

Vrach Delo. 1990 Jun(6):70-2.

PMID:2399728
Abstract

The levels of carbohydrate metabolism were examined in 329 inhabitants of Lvov (age: from 6 to 68 years). Determination of the pyruvate level, pyruvate dehydrogenase activity of the blood on the 120 minute after carbohydrate meal allowed to establish in healthy persons four-modal levels of distribution of the content of pyruvate in the capillary blood. These levels correspond to normal tolerance to glucose, increased glucose tolerance (hyperinsulinism), potential glucose tolerance disorders (diabetic type). The authors propose a chart of prophylactic evaluation of glucose tolerance.

摘要

对利沃夫的329名居民(年龄6至68岁)的碳水化合物代谢水平进行了检测。通过测定碳水化合物餐后120分钟时血液中的丙酮酸水平和丙酮酸脱氢酶活性,得以在健康人群中确定毛细血管血中丙酮酸含量的四种模式分布水平。这些水平分别对应对葡萄糖的正常耐受性、葡萄糖耐受性增加(高胰岛素血症)、潜在的葡萄糖耐受性紊乱(糖尿病类型)。作者提出了一份葡萄糖耐受性预防性评估图表。

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