Hetem S, Kollar E J, Cutler L S, Yaeger J A
J Dent Res. 1975 Jul-Aug;54(4):783-7. doi: 10.1177/00220345750540041501.
Dipyridyl inhibits the morphogenesis of tooth germs, but the germs recover when transferred to control medium. In this study, the effect of dipyridyl on basement membrane was investigated in vitro. The basal lamina was always present, but the subjacent collagen fibrils disappeared in the presence of dipyridyl and reappeared during recovery in control medium.
联吡啶抑制牙胚的形态发生,但当转移至对照培养基中时,牙胚会恢复。在本研究中,体外研究了联吡啶对基底膜的影响。基底层始终存在,但在联吡啶存在的情况下,其下方的胶原纤维消失,并在对照培养基中恢复过程中重新出现。