Kadel C, Richter J, Klepzig H, Kober G, Kaltenbach M
Abteilung für Kardiologie, Universität Frankfurt.
Z Kardiol. 1990 Jul;79(7):512-7.
To determine the long-term clinical course after percutaneous transluminal coronary angioplasty (PTCA), 841 patients, 615 with successful PTCA and 226 without, were restudied by questionnaire 2-9 years after the intervention. After successful PTCA a lasting symptomatic improvement was seen in 78% of patients vs 55% of patients without successful PTCA (p less than 0.0001). The probability of myocardial infarction 8 years after successful PTCA was 6% vs 24% after unsuccessful PTCA (p less than 0.0005). The 8-year survival probability (non-cardiac deaths excluded) was 95.7% in patients with demonstrable PTCA success, and 92.0% in patients without (p less than 0.05). Similar significant differences in favor of patients with successful PTCA were seen in the long-term prognosis of patients with single-vessel disease (n = 580). It is concluded that a long-term improvement of the cardiac prognosis by successful PTCA is probable.
为了确定经皮腔内冠状动脉成形术(PTCA)后的长期临床病程,在干预2至9年后,通过问卷调查对841例患者进行了再次研究,其中615例PTCA成功,226例PTCA未成功。PTCA成功后,78%的患者症状持续改善,而PTCA未成功的患者中这一比例为55%(p<0.0001)。PTCA成功后8年发生心肌梗死的概率为6%,而PTCA未成功后为24%(p<0.0005)。PTCA成功的患者8年生存概率(不包括非心脏性死亡)为95.7%,PTCA未成功的患者为92.0%(p<0.05)。在单支血管病变患者(n=580)的长期预后中,也观察到了有利于PTCA成功患者的类似显著差异。得出的结论是,PTCA成功可能会长期改善心脏预后。