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本文引用的文献

1
Postoperative pain following coblation tonsillectomy: randomized clinical trial.低温等离子体扁桃体切除术后的疼痛:随机临床试验
ANZ J Surg. 2006 Apr;76(4):226-9. doi: 10.1111/j.1445-2197.2006.03700.x.
2
Radiofrequency excision versus monopolar electrosurgical excision for tonsillectomy.扁桃体切除术的射频切除与单极电刀切除对比
Otolaryngol Head Neck Surg. 2005 Jul;133(1):51-4. doi: 10.1016/j.otohns.2005.02.013.
3
A double-blinded randomized controlled trial of coblation versus conventional dissection tonsillectomy on post-operative symptoms.一项关于低温等离子消融术与传统剥离法扁桃体切除术术后症状的双盲随机对照试验。
Clin Otolaryngol. 2005 Apr;30(2):143-8. doi: 10.1111/j.1365-2273.2004.00953.x.
4
Randomized controlled trial of Coblation versus electrocautery tonsillectomy.等离子刀与电灼扁桃体切除术的随机对照试验
Otolaryngol Head Neck Surg. 2005 Feb;132(2):273-80. doi: 10.1016/j.otohns.2004.11.002.
5
Postoperative tonsillectomy bleed: coblation versus noncoblation.扁桃体切除术后出血:低温等离子消融术与非低温等离子消融术对比
Laryngoscope. 2005 Jan;115(1):31-3. doi: 10.1097/01.mlg.0000150682.62517.0e.
6
Randomized, controlled, multisite study of intracapsular tonsillectomy using low-temperature plasma excision.使用低温等离子体切除术进行囊内扁桃体切除术的随机、对照、多中心研究。
Arch Otolaryngol Head Neck Surg. 2004 Nov;130(11):1303-7. doi: 10.1001/archotol.130.11.1303.
7
Pediatric total tonsillectomy using coblation compared to conventional electrosurgery: a prospective, controlled single-blind study.与传统电外科手术相比,使用低温等离子刀进行小儿全扁桃体切除术:一项前瞻性、对照单盲研究。
Otolaryngol Head Neck Surg. 2004 Jun;130(6):666-75. doi: 10.1016/j.otohns.2004.02.012.
8
Radiofrequency ablation versus electrocautery in tonsillectomy.扁桃体切除术中射频消融与电灼术的比较
Otolaryngol Head Neck Surg. 2004 Mar;130(3):300-5. doi: 10.1016/j.otohns.2003.09.024.
9
Coblation tonsillectomy versus dissection tonsillectomy: postoperative hemorrhage.低温等离子体扁桃体切除术与剥离扁桃体切除术:术后出血
Laryngoscope. 2003 Nov;113(11):2010-3. doi: 10.1097/00005537-200311000-00029.
10
Increased post-operative haemorrhage seen in adult coblation tonsillectomy.成人低温等离子体扁桃体切除术后出血增加。
J Laryngol Otol. 2003 Sep;117(9):704-6. doi: 10.1258/002221503322334521.

一项针对成年患者的前瞻性、随机、双盲研究:对比低温等离子刀扁桃体切除术与剥离法扁桃体切除术

A Prospective, Randomized, Double-Blind Study of Coblation versus Dissection Tonsillectomy in Adult Patients.

作者信息

Rakesh Singh, Anand T S, Payal Garg, Pranjal Kulshreshtha

机构信息

Department of Otorhinolaryngology, LHMC & Associated Hospitals, New Delhi, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2012 Sep;64(3):290-4. doi: 10.1007/s12070-011-0355-y. Epub 2011 Nov 30.

DOI:10.1007/s12070-011-0355-y
PMID:23998038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3431530/
Abstract

This randomized double blind study was conducted prospectively to determine whether coblation tonsillectomy fared better than the conventional dissection method in terms of postoperative pain, bleeding, and rapidity of healing in adult Indian patients undergoing tonsillectomy. Sixty adult patients undergoing tonsillectomy for benign indications were randomized to have one tonsil removed by subcapsular radiofrequency ablation method and the other by conventional dissection method. The operative time and blood loss was noted for each side. Patients were evaluated at 6, 12, 24, 48, 72 h and then on 7th and 20th postoperative day for postoperative pain (by visual analog scale), bleeding, and tonsillar fossa healing. Statistical comparison was done using appropriate tests. The two groups were demographically matched. It took longer to perform the coblation procedure (15 vs 11 min) (P > 0.05). The operative blood loss on the radiofrequency side was 11 ml, vs 34 ml on the conventional side (P = 0.009). 77% patients said that the coblation side was less painful for the overall 20-day recovery period. There were significant differences seen at 6, 12, 24, 48, and 72 h in terms of postoperative pain scores. Beyond that, the pain was consistently less on the coblation side, but the difference was not significant. There was no case of reactionary or secondary hemorrhage in either arm. The healing took longer on the radiofrequency side. Coblation tonsillectomy is an easy to learn technique with significantly reduced operative blood loss and postoperative pain. Longer operative times maybe further reduced with experience.

摘要

本前瞻性随机双盲研究旨在确定在接受扁桃体切除术的成年印度患者中,低温等离子扁桃体切除术在术后疼痛、出血及愈合速度方面是否优于传统剥离法。60例因良性指征接受扁桃体切除术的成年患者被随机分为两组,一侧扁桃体采用包膜下射频消融法切除,另一侧采用传统剥离法切除。记录每侧的手术时间和失血量。在术后6、12、24、48、72小时以及术后第7天和第20天对患者进行评估,评估指标包括术后疼痛(采用视觉模拟评分法)、出血情况及扁桃体窝愈合情况。使用适当的检验方法进行统计学比较。两组在人口统计学特征上相匹配。低温等离子手术耗时更长(15分钟对11分钟)(P>0.05)。射频消融侧的手术失血量为11毫升,而传统方法侧为34毫升(P = 0.009)。77%的患者表示在整个20天的恢复期内,低温等离子侧的疼痛较轻。在术后疼痛评分方面,6、12、24、48和72小时时两组有显著差异。除此之外,低温等离子侧的疼痛一直较轻,但差异不显著。两组均无继发性出血或反应性出血病例。射频消融侧的愈合时间更长。低温等离子扁桃体切除术是一种易于学习的技术,可显著减少手术失血量和术后疼痛。随着经验的积累,较长的手术时间可能会进一步缩短。