三级医疗中心胎儿异常的发生率。
Frequency of foetal anomalies in a tertiary care centre.
作者信息
Babu Rameswarapu Suman, Pasula Sujatha
机构信息
Associate Professor, Department of Anatomy, Mediciti Institute of Medical Sciences , Ghanpur, Ranga Reddy District-501401, Andhra Pradesh, India .
出版信息
J Clin Diagn Res. 2013 Jul;7(7):1276-9. doi: 10.7860/JCDR/2013/6336.3187. Epub 2013 Jul 1.
OBJECTIVE
The present study was undertaken to explore the incidence of congenital foetal anomalies and the advantages of ultrasonography in detecting the foetal anomalies during the antenatal period.
METHOD
We focused our study on 1000 consecutive pregnancies that came for check up in the second and third trimesters, with major or minor clinically relevant malformations which were detectable by ultrasonography.
RESULTS
The analysis revealed that they were 38 foetal anomalies in 37 foetuses. One had multiple anomalies, with the highest incidence of neural tube defects. There was also significant correlation with consanguinity.
CONCLUSION
The overall incidence of congenital foetal anomalies in the present study was 3.8%.This might be probably due to environmental pollution, radiation, exposure to different chemicals and teratogenic drugs.
目的
本研究旨在探讨先天性胎儿异常的发生率以及超声检查在产前检测胎儿异常方面的优势。
方法
我们的研究集中于1000例在孕中期和孕晚期前来检查的连续妊娠病例，这些病例存在可通过超声检查检测到的严重或轻微的临床相关畸形。
结果
分析显示，37例胎儿中有38处胎儿异常。1例有多种异常，其中神经管缺陷的发生率最高。近亲结婚也存在显著相关性。
结论
本研究中先天性胎儿异常的总体发生率为3.8%。这可能是由于环境污染、辐射、接触不同化学物质和致畸药物所致。
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