• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

睾丸非精原性混合性生殖细胞肿瘤中的畸胎癌——一种罕见的实体。

Teratocarcinoma in a non seminomatous, mixed germ cell tumour of the testis-a rare entity.

作者信息

Malavalli Gayathri, Karra Shilpa, Muniyappa Bharathi

机构信息

Assistant Professor, Department of Pathology.

出版信息

J Clin Diagn Res. 2013 Jul;7(7):1439-40. doi: 10.7860/JCDR/2013/5404.3161. Epub 2013 Jul 1.

DOI:10.7860/JCDR/2013/5404.3161
PMID:23998086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3749656/
Abstract

Mixed Germ Cell Tumours (MGCTs) of the testis are the second most common testicular tumours. In the 10 years retrospective study which was done on testicular neoplasms at our institute, this reported case accounted for 0.4%. We are presenting the case of a 30 year old male with a painless testicular swelling. Abdominal ultrasonography disclosed it as a seminoma and the FNAC report was Mixed Germ Cell tumour of the testis. Histopathology concurred the cytological diagnosis and it additionally revealed the concomitant presence of a Yolk Sac Tumour (YST) and a Teratocarcinoma in a Non-Seminomatous Tumour of the testis. This case attains uniqueness with the very rare presence of the yolk sac tumour with the teratocarcinoma component in Non-Seminomatous Testicular Tumours. The reason behind the reporting of the case was its poor therapeutic response.

摘要

睾丸混合性生殖细胞肿瘤(MGCTs)是第二常见的睾丸肿瘤。在我们研究所对睾丸肿瘤进行的10年回顾性研究中,该报告病例占0.4%。我们报告一例30岁男性,有无痛性睾丸肿大。腹部超声检查显示为精原细胞瘤,细针穿刺活检(FNAC)报告为睾丸混合性生殖细胞肿瘤。组织病理学与细胞学诊断一致,此外还显示在睾丸非精原细胞瘤中同时存在卵黄囊瘤(YST)和畸胎癌。该病例因在睾丸非精原细胞瘤中罕见地同时存在卵黄囊瘤和畸胎癌成分而独具特色。报告该病例的原因是其治疗反应不佳。

相似文献

1
Teratocarcinoma in a non seminomatous, mixed germ cell tumour of the testis-a rare entity.睾丸非精原性混合性生殖细胞肿瘤中的畸胎癌——一种罕见的实体。
J Clin Diagn Res. 2013 Jul;7(7):1439-40. doi: 10.7860/JCDR/2013/5404.3161. Epub 2013 Jul 1.
2
A unique case of a sarcoma arising in a testicular non-seminomatous mixed germ cell tumour with a predominant yolk sac component.一例罕见病例,肉瘤发生于睾丸非精原性混合性生殖细胞肿瘤,以卵黄囊成分占主导。
Can Urol Assoc J. 2011 Oct;5(5):E81-3. doi: 10.5489/cuaj.10069.
3
Impact of classification of mixed germ-cell tumours on incidence trends of non-seminoma.混合性生殖细胞肿瘤分类对非精原细胞瘤发病率趋势的影响。
Int J Androl. 2011 Aug;34(4 Pt 2):e274-7. doi: 10.1111/j.1365-2605.2011.01187.x. Epub 2011 May 30.
4
The Clinical Significance of Seminoma Component in Testicular Mixed Germ Cell Tumour.精原细胞瘤成分在睾丸混合性生殖细胞肿瘤中的临床意义。
Urol Int. 2020;104(5-6):489-496. doi: 10.1159/000506780. Epub 2020 Apr 2.
5
Activated status of tumour-infiltrating lymphocytes and apoptosis in testicular seminoma.睾丸精原细胞瘤中肿瘤浸润淋巴细胞的活化状态与细胞凋亡
J Pathol. 2002 Jan;196(1):67-75. doi: 10.1002/path.996.
6
Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report.一名患有单侧隐睾症的不育男性的混合性生殖细胞肿瘤:一例罕见病例报告。
J Clin Diagn Res. 2016 Feb;10(2):PD17-8. doi: 10.7860/JCDR/2016/15298.7238. Epub 2016 Feb 1.
7
Pitfalls in the interpretation of specimens from patients with testicular tumours, with an emphasis on variant morphologies.睾丸肿瘤患者标本解读中的陷阱,重点是各种变异形态。
Pathology. 2018 Jan;50(1):88-99. doi: 10.1016/j.pathol.2017.07.013. Epub 2017 Nov 10.
8
Wnt suppressor and stem cell regulator TCF7L1 is a sensitive immunohistochemical marker to differentiate testicular seminoma from non-seminomatous germ cell tumor.Wnt 抑制因子和干细胞调节因子 TCF7L1 是一种敏感的免疫组织化学标志物,可用于区分睾丸精原细胞瘤与非精原细胞瘤生殖细胞肿瘤。
Exp Mol Pathol. 2019 Oct;110:104293. doi: 10.1016/j.yexmp.2019.104293. Epub 2019 Aug 2.
9
Immunohistochemical expression of monoclonal antibody 43-9F in testicular germ cell tumours.单克隆抗体43-9F在睾丸生殖细胞肿瘤中的免疫组化表达
Int J Androl. 1998 Oct;21(5):283-8. doi: 10.1046/j.1365-2605.1998.00131.x.
10
Extra embryonic elements in testicular tumours.睾丸肿瘤中的胚外成分。
Int J Androl. 1981 Mar;4 Suppl s4:35-48. doi: 10.1111/j.1365-2605.1981.tb00649.x.

引用本文的文献

1
Neuroscience of cancer: Research progress and emerging of the field.癌症神经科学:该领域的研究进展与新进展
Ibrain. 2024 Aug 14;10(3):305-322. doi: 10.1002/ibra.12172. eCollection 2024 Fall.
2
The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells.HERV-K 辅助蛋白 Np9 控制畸胎癌细胞的活力和迁移。
PLoS One. 2019 Feb 28;14(2):e0212970. doi: 10.1371/journal.pone.0212970. eCollection 2019.

本文引用的文献

1
Malignant transformation of testicular teratoma: a chemoresistant phenotype.睾丸畸胎瘤的恶性转化:一种化疗耐药表型。
Urol Oncol. 2008 Nov-Dec;26(6):595-9. doi: 10.1016/j.urolonc.2007.07.013. Epub 2008 Jan 14.
2
Global cancer statistics, 2002.2002年全球癌症统计数据。
CA Cancer J Clin. 2005 Mar-Apr;55(2):74-108. doi: 10.3322/canjclin.55.2.74.
3
Histology in mixed germ cell tumors. Is there a favorite pairing?混合性生殖细胞肿瘤的组织学。是否存在常见的组合?
J Urol. 2004 Apr;171(4):1471-3. doi: 10.1097/01.ju.0000116841.30826.85.
4
Chemotherapy for teratoma with malignant transformation.恶性转化性畸胎瘤的化疗
J Clin Oncol. 2003 Dec 1;21(23):4285-91. doi: 10.1200/JCO.2003.01.019.
5
Prognostic features of teratomas with malignant transformation: a clinicopathological study of 21 cases.畸胎瘤恶变的预后特征:21例临床病理研究
J Urol. 1998 Mar;159(3):859-63.
6
Adult primary pure teratoma of the testis. The Indiana experience.成人睾丸原发性纯畸胎瘤。印第安纳州的经验。
Cancer. 1995 May 1;75(9):2244-50. doi: 10.1002/1097-0142(19950501)75:9<2244::aid-cncr2820750909>3.0.co;2-i.
7
The incidence of yolk sac tumor (endodermal sinus tumor) elements in germ cell tumors of the testis in adults.成人睾丸生殖细胞肿瘤中卵黄囊瘤(内胚窦瘤)成分的发生率。
Cancer. 1975 Jul;36(1):211-5. doi: 10.1002/1097-0142(197507)36:1<211::aid-cncr2820360122>3.0.co;2-w.