Department of Laser Studies, School of Physics, Madurai Kamaraj University, Madurai, Tamilnadu, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jan 3;117:299-303. doi: 10.1016/j.saa.2013.07.064. Epub 2013 Aug 3.
The pure hydroxyapatite (HAP) nanoparticles (NPs) have been synthesized by wet chemical precipitation method. Raman spectral measurements have been made for pure HAP, pure Polyethylene glycol (PEG) 6000 and PEG coated HAP in different mass ratios (sample 1, sample 2 and sample 3). The peaks observed in Raman spectrum of pure HAP and the XRD pattern have confirmed the formation of HAP NPs. Vibrational modes have been assigned for pure HAP and pure PEG 6000. The observed variation in peak position of Raman active vibrational modes of PEG in PEG coated HAP has been elucidated in this work, in terms of intermolecular interactions between PEG and HAP. Further these results suggest that the functionalization of nanoparticles may be independent of PEG mass.
通过湿化学沉淀法合成了纯羟基磷灰石（HAP）纳米粒子（NPs）。对纯 HAP、纯聚乙二醇（PEG）6000 和不同质量比的 PEG 涂覆的 HAP（样品 1、样品 2 和样品 3）进行了 Raman 光谱测量。Raman 光谱中观察到的纯 HAP 和 XRD 图谱中的峰证实了 HAP NPs 的形成。为纯 HAP 和纯 PEG 6000 分配了振动模式。本文阐述了在 PEG 涂覆的 HAP 中 PEG 的 Raman 活性振动模式的峰位置观察到的变化，这是基于 PEG 和 HAP 之间的分子间相互作用。此外，这些结果表明纳米粒子的功能化可能与 PEG 的质量无关。
