Katkovskiĭ D G, Stepanova N A
Anesteziol Reanimatol. 1990 Mar-Apr(2):51-4.
To determine principles of choosing individual fentanyl and ketamin doses the data on the course of general anesthesia in 120 children were processed by regression analysis. It has been established that individual anesthetic dose titration should take into consideration the child's age, efficacy of premedication, renal function and circulatory pattern The infusion rate is determined with regard to anesthesia-induced circulatory changes. Regression analysis made it possible to work out formulas which enable individual dose titration and determination of the infusion rate.
为确定选择个体芬太尼和氯胺酮剂量的原则,对120例儿童全身麻醉过程中的数据进行回归分析。结果表明,个体麻醉剂量滴定应考虑儿童年龄、术前用药效果、肾功能和循环模式。输注速率根据麻醉引起的循环变化来确定。回归分析使制定出能够进行个体剂量滴定和确定输注速率的公式成为可能。