采用导数紫外分光光度法测定硝苯地平原料药及制剂中2,6-二甲基-4-(2'-亚硝基苯基)-3,5-吡啶二甲酸二甲酯的含量。
Determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine by derivative UV-spectrophotometry in bulk material and pharmaceutical forms.
作者信息
Carlucci G, Colanzi A, Mazzeo P
机构信息
Dipartimento di Chimica, Università dell'Aquila, Italy.
出版信息
Farmaco. 1990 Jun;45(6 Suppl):751-5.
PMID:2400525
Abstract
A method for the determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine (bulk material and pharmaceutical formulations) by second-derivative ultraviolet spectrophotometry is described. The procedure is simple and rapid and gives accurate and precise results.
摘要
描述了一种用二阶导数紫外分光光度法测定硝苯地平（原料药和药物制剂）中2,6-二甲基-4-(2'-亚硝基苯基)-3,5-吡啶二甲酸二甲酯的方法。该方法简单快速，结果准确精密。
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