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腹腔镜与开放手术治疗原发性腹外疝的结果比较。

Outcomes of laparoscopic vs open repair of primary ventral hernias.

机构信息

Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.

出版信息

JAMA Surg. 2013 Nov;148(11):1043-8. doi: 10.1001/jamasurg.2013.3587.

Abstract

IMPORTANCE

More primary ventral hernias (PVHs) are being repaired using the technique of laparoscopic ventral hernia repair (LVHR). Few studies exist comparing the outcomes of LVHR with the outcomes of open ventral hernia repair (OVHR) for PVHs. We hypothesize that LVHR of PVHs is associated with fewer surgical site infections (SSIs) but more hernia recurrences and more clinical cases of bulging (bulging not associated with recurrence or seroma).

OBJECTIVE

To compare the outcomes of patients who underwent LVHR with the outcomes of patients who underwent OVHR.

DESIGN

Retrospective study of 532 consecutive patients who underwent an elective PVH repair at a single institution from 2000 to 2010. The outcomes of the 2 procedures were compared using 2 statistical methods. Multivariable logistic regression was used to evaluate the association between outcomes and several independent factors, adjusting for treatment propensity, and the outcomes in the 2 groups of patients were compared using paired univariate analysis.

SETTING

Michael E. DeBakey VA Medical Center in Houston, Texas.

PARTICIPANTS

Seventy-nine patients who underwent LVHR and 79 patients who underwent OVHR.

MAIN OUTCOMES AND MEASURES

The primary outcomes of interest were SSI, hernia recurrence, and bulging. The 2 groups of patients were matched by hernia size, American Society of Anesthesiologists class, age, and body mass index.

RESULTS

There were 91 patients who underwent an LVHR and 167 patients who underwent an OVHR with mesh, with a median follow-up period of 56 months (range, 1-156 months). Seventy-nine patients with an LVHR were matched to 79 patients with an OVHR. No significant differences in demographic data or confounding factors were detected between the 2 groups. Compared with OVHR, LVHR was significantly associated with fewer SSIs (7.6% vs 34.1%; P < .01) but more clinical cases of bulging (21.5% vs 1.3%; P < .01) and port-site hernia (2.5% vs 0.0%). No differences in recurrence at the site of the hernia repair were observed (11.4% vs 11.4%; P = .99). Propensity score-matched multivariate analysis corroborated that LVHR is associated with more clinical cases of bulging but fewer SSIs.

CONCLUSIONS AND RELEVANCE

Compared with OVHR of PVHs, LVHR of PVHs is associated with fewer SSIs but more clinical cases of bulging and with the risk of developing a port-site hernia. Further study is needed to clarify the role of LVHR of PVHs and to mitigate the risk of port-site hernia and bulging.

摘要

重要性

越来越多的原发性腹侧疝(PVH)采用腹腔镜腹侧疝修补术(LVHR)进行修复。比较 LVHR 和开放式腹侧疝修补术(OVHR)治疗 PVH 结果的研究较少。我们假设 PVH 的 LVHR 与较少的手术部位感染(SSI)相关,但疝复发和更多的临床隆起病例(隆起与复发或血清肿无关)更多。

目的

比较行 LVHR 的患者与行 OVHR 的患者的结局。

设计

对 2000 年至 2010 年在单一机构接受择期 PVH 修复的 532 例连续患者进行回顾性研究。使用 2 种统计方法比较 2 种手术的结果。多变量逻辑回归用于评估结局与多个独立因素之间的关联,同时调整治疗倾向,使用配对单变量分析比较两组患者的结局。

地点

德克萨斯州休斯顿迈克尔·E·德贝基退伍军人事务医疗中心。

参与者

79 例接受 LVHR 和 79 例接受 OVHR 的患者。

主要结局和措施

主要感兴趣的结局是 SSI、疝复发和隆起。两组患者通过疝大小、美国麻醉医师学会(ASA)分级、年龄和体重指数匹配。

结果

有 91 例患者接受 LVHR 和 167 例患者接受 OVHR 加网片治疗,中位随访时间为 56 个月(范围,1-156 个月)。79 例 LVHR 患者与 79 例 OVHR 患者相匹配。两组患者在人口统计学数据或混杂因素方面无显著差异。与 OVHR 相比,LVHR 与 SSI 显著减少相关(7.6%比 34.1%;P <.01),但临床隆起病例(21.5%比 1.3%;P <.01)和端口部位疝(2.5%比 0.0%)更多。未观察到疝修复部位复发的差异(11.4%比 11.4%;P =.99)。倾向评分匹配的多变量分析证实,LVHR 与更多的临床隆起病例相关,但 SSI 较少。

结论和相关性

与 PVH 的 OVHR 相比,PVH 的 LVHR 与较少的 SSI 相关,但更多的临床隆起病例和端口部位疝的风险。需要进一步研究以阐明 PVH 的 LVHR 的作用,并降低端口部位疝和隆起的风险。

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