McWalter Emily J, O'Kane Colm M, Fitzpatrick David P, Wilson David R
Department of Mechanical Engineering, University of British Columbia, Vancouver, British Columbia, Canada.
J Magn Reson Imaging. 2014 Apr;39(4):978-87. doi: 10.1002/jmri.24240. Epub 2013 Sep 4.
To develop and validate short axial and sagittal MRI scans (<1min) to assess in vivo patellofemoral contact areas in loaded knee flexion.
Contact area was assessed in four cadaver knee specimens from axial and sagittal scans using two contact area extraction techniques (delineation and intersection) and three calculation techniques (slice thickness multiplication, linear interpolation, and spline interpolation). Error was expressed as the mean absolute and percentage difference from a dye staining-based reference standard. Intrareader and intrasubject repeatability, expressed as the mean standard deviation, was determined.
Contact area assessments from the sagittal MRI scans using the delineation and slice thickness multiplication technique had the smallest error (47.7 ± 38.1 mm(2) or 10.7%). The intrareader repeatability from assessments using the sagittal scans was smaller than those using the axial scans when the delineation method was used (<9.4 ± 4.3 mm(2) and <15.4 ± 14.1 mm(2) , respectively). The intrasubject repeatability of the assessment from the sagittal scan was less than 39.9 ± 23.0 mm(2) .
This protocol yields assessments of contact area in less than 1 minute that have errors similar to those made using scans many times longer and can be used in series with kinematic scans to carry out simultaneous assessments in vivo to study patellofemoral joint disease.
开发并验证短时间的轴向和矢状面MRI扫描(<1分钟),以评估负重膝关节屈曲时体内髌股关节的接触面积。
使用两种接触面积提取技术(描绘法和相交法)以及三种计算技术(切片厚度相乘、线性插值和样条插值),对四个尸体膝关节标本的轴向和矢状面扫描图像进行接触面积评估。误差表示为与基于染料染色的参考标准相比的平均绝对差值和百分比差值。确定了阅片者内和受试者内的重复性,以平均标准差表示。
使用描绘法和切片厚度相乘技术对矢状面MRI扫描图像进行接触面积评估时误差最小(47.7±38.1mm²或10.7%)。当使用描绘法时,使用矢状面扫描进行评估的阅片者内重复性小于使用轴向扫描的情况(分别为<9.4±4.3mm²和<15.4±14.1mm²)。矢状面扫描评估的受试者内重复性小于39.9±23.0mm²。
该方案可在不到1分钟的时间内完成接触面积评估,其误差与使用时长数倍于此的扫描所产生的误差相似,可与运动扫描序列联用,在体内进行同步评估以研究髌股关节疾病。