Hof H
Labor Limbach, Heidelberg.
Pneumologie. 2013 Sep;67(9):509-12. doi: 10.1055/s-0033-1344491. Epub 2013 Sep 4.
As typical opportunistic pathogens fungi, for example Pneumocystis jirovecii, infect predominantly immunocompromised hosts. There are, however, others, for example Coccidioides immitis and Cryptococcus neoformans, which endanger otherwise healthy people, too. Fungi are not mentioned as causative agents of pneumonias in the german guidelines for community acquired pneumonia. In the german guidelines for nosocomial pneumonia only very few, namely Aspergillus spp. and Candida spp., are shortly discussed. In case of severe courses of community-acquired pneumonias especially in patients with co-morbidities, which do not respond adequately to antibacterial therapy, fungi have to be included in the differential diagnostic considerations.
作为典型的机会性病原体,真菌,例如耶氏肺孢子菌,主要感染免疫功能低下的宿主。然而,也有其他一些真菌,例如粗球孢子菌和新型隐球菌,它们也会危及原本健康的人。在德国社区获得性肺炎指南中未提及真菌作为肺炎的病原体。在德国医院获得性肺炎指南中,仅简短讨论了极少数真菌,即曲霉属和念珠菌属。对于社区获得性肺炎的严重病程,尤其是在患有合并症且对抗菌治疗反应不佳的患者中,必须将真菌纳入鉴别诊断的考虑范围。