Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee.
J Surg Oncol. 2013 Dec;108(7):477-80. doi: 10.1002/jso.23427. Epub 2013 Sep 4.
Soft tissue sarcomas (STS) continue to be excised inappropriately without proper preoperative planning. The reasons for this remain elusive. The role of insurance status and patient distance from sarcoma center in influencing such inappropriate excisions were examined in this study.
This retrospective review of a single institution prospective database evaluated 400 patients treated for STS of the extremities between January 2000 and December 2008. Two hundred fifty three patients had a primary excision while 147 patients underwent re-excision. Wilcoxon rank sum test and either χ(2) or Fisher's exact were used to compare variables. Multivariable regression analyses were used to take into account potential confounders and identify variables that affected excision status.
Tumor size, site, depth, stage, margins, and histology were significantly different between the primary excision and re-excision groups; P < 0.05. Insurance status and patient distance from the treatment center were not statistically different between the two groups. Large and deep tumors and certain histology types predicted appropriate referral.
Inappropriate excision of STS is not influenced by patient distance from a sarcoma center or by a patient's insurance status. In this study, tumor size, depth, and certain histology types predicted the appropriate referral of a STS to a sarcoma center.
软组织肉瘤(STS)在没有适当术前计划的情况下仍被不当切除。造成这种情况的原因尚不清楚。本研究旨在探讨保险状况和患者距肉瘤中心的距离对影响这种不适当切除的作用。
本研究回顾性分析了一家单机构前瞻性数据库中 2000 年 1 月至 2008 年 12 月期间治疗的四肢 STS 患者 400 例。253 例患者行初次切除术,147 例患者行再次切除术。Wilcoxon 秩和检验和 χ(2)或 Fisher 确切概率法用于比较变量。多变量回归分析用于考虑潜在混杂因素,并确定影响切除状态的变量。
肿瘤大小、部位、深度、分期、切缘和组织学在初次切除术和再次切除术组之间有显著差异;P < 0.05。两组患者的保险状况和距治疗中心的距离无统计学差异。大肿瘤和深肿瘤以及某些组织学类型预示着适当的转诊。
STS 的不当切除不受患者距肉瘤中心的距离或患者保险状况的影响。在本研究中,肿瘤大小、深度和某些组织学类型预测了 STS 向肉瘤中心的适当转诊。