Cheminformatics and Metabolism, European Bioinformatics Institute, Cambridge, UK, Swiss Center for Affective Sciences, University of Geneva, Geneva, Switzerland and Evolutionary Bioinformatics, Swiss Institute of Bioinformatics, Lausanne, Romandy, Switzerland.
Bioinformatics. 2013 Nov 15;29(22):2955-7. doi: 10.1093/bioinformatics/btt514. Epub 2013 Sep 5.
The Web Ontology Language (OWL) provides a sophisticated language for building complex domain ontologies and is widely used in bio-ontologies such as the Gene Ontology. The Protégé-OWL ontology editing tool provides a query facility that allows composition and execution of queries with the human-readable Manchester OWL syntax, with syntax checking and entity label lookup. No equivalent query facility such as the Protégé Description Logics (DL) query yet exists in web form. However, many users interact with bio-ontologies such as chemical entities of biological interest and the Gene Ontology using their online Web sites, within which DL-based querying functionality is not available. To address this gap, we introduce the OntoQuery web-based query utility.
The source code for this implementation together with instructions for installation is available at http://github.com/IlincaTudose/OntoQuery. OntoQuery software is fully compatible with all OWL-based ontologies and is available for download (CC-0 license). The ChEBI installation, ChEBI OntoQuery, is available at http://www.ebi.ac.uk/chebi/tools/ontoquery.
Web 本体语言 (OWL) 提供了一种用于构建复杂领域本体的复杂语言,并且在基因本体等生物本体中被广泛使用。Protégé-OWL 本体编辑工具提供了一个查询功能,允许使用人类可读的曼彻斯特 OWL 语法组合和执行查询,同时进行语法检查和实体标签查找。目前还没有像 Protégé 描述逻辑 (DL) 查询这样的等效查询功能以 Web 表单的形式存在。然而,许多用户通过其在线网站与生物本体(例如生物感兴趣的化学实体和基因本体)进行交互,而这些在线网站不提供基于 DL 的查询功能。为了解决这个差距,我们引入了基于 Web 的 OntoQuery 查询实用程序。
这个实现的源代码以及安装说明可以在 http://github.com/IlincaTudose/OntoQuery 上找到。OntoQuery 软件与所有基于 OWL 的本体完全兼容,可下载使用(CC-0 许可证)。ChEBI 安装程序 ChEBI OntoQuery 可在 http://www.ebi.ac.uk/chebi/tools/ontoquery 上找到。