Hoehndorf Robert, Slater Luke, Schofield Paul N, Gkoutos Georgios V
Computational Bioscience Research Center, King Abdullah University of Science and Technology, 4700 KAUST, Thuwal, 23955-6900, Saudi Arabia.
Computer, Electrical and Mathematical Sciences & Engineering Division, King Abdullah University of Science and Technology, 4700 KAUST, Thuwal, 23955-6900, Saudi Arabia.
BMC Bioinformatics. 2015 Jan 28;16:26. doi: 10.1186/s12859-015-0456-9.
Many ontologies have been developed in biology and these ontologies increasingly contain large volumes of formalized knowledge commonly expressed in the Web Ontology Language (OWL). Computational access to the knowledge contained within these ontologies relies on the use of automated reasoning.
We have developed the Aber-OWL infrastructure that provides reasoning services for bio-ontologies. Aber-OWL consists of an ontology repository, a set of web services and web interfaces that enable ontology-based semantic access to biological data and literature. Aber-OWL is freely available at http://aber-owl.net .
Aber-OWL provides a framework for automatically accessing information that is annotated with ontologies or contains terms used to label classes in ontologies. When using Aber-OWL, access to ontologies and data annotated with them is not merely based on class names or identifiers but rather on the knowledge the ontologies contain and the inferences that can be drawn from it.
生物学领域已经开发了许多本体,这些本体越来越多地包含大量以网络本体语言(OWL)形式表达的形式化知识。对这些本体中所含知识的计算访问依赖于自动推理的使用。
我们开发了Aber-OWL基础设施,它为生物本体提供推理服务。Aber-OWL由一个本体存储库、一组网络服务和网络接口组成,这些服务和接口实现了基于本体的对生物数据和文献的语义访问。可通过http://aber-owl.net免费获取Aber-OWL。
Aber-OWL提供了一个自动访问用本体注释的信息或包含用于标记本体中类的术语的信息的框架。使用Aber-OWL时,对本体及其注释数据的访问不仅仅基于类名或标识符,而是基于本体所包含的知识以及从中可以得出的推论。