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十二指肠结核——一例罕见病例报告及文献综述

Duodenal tuberculosis--a rare case report and review of literature.

作者信息

Dahiya Divya, Garg Mandeep, Kaman Lileswar, Rana Surinder, Rao Chalapathi, Behera Arunanshu

出版信息

Pol Przegl Chir. 2013 Aug;85(8):464-6. doi: 10.2478/pjs.2013.85.8.464.

DOI:10.2478/pjs.2013.85.8.464
PMID:24009058
Abstract

Extrapulmonary tuberculosis is rare and often difficult to diagnose infection. We report a case of duodenal tuberculosis, who presented with upper gastrointestinal symptoms. There was evidence of obstruction in the third part of duodenum (D3) on oesophagogastro endoscopy, barium meal follow through and CT scan of abdomen. On exploration there was thickening of D3 and D4 causing luminal obstruction. Resection of stricturous segment with end-to-side duodenojejunostomy was done. Biopsy of the diseased segment was tubercular. Antitubercular treatment was given to the patient for 6 months and he is doing well on follow up (1 year after surgery). Duodenal tuberculosis being the rarest form of intestinal tuberculosis poses great difficulty in diagnosis. High index of suspicion supported by radiological investigation, exploratory laparotomy and histopathological examination of the tissue can only lead to a definitive diagnosis of this rare condition. Treatment is both surgical which involves resection or by-pass for an obstructive lesion and medical which includes antitubercular therapy.

摘要

肺外结核较为罕见,且感染常难以诊断。我们报告一例十二指肠结核病例,该患者表现为上消化道症状。食管胃十二指肠镜检查、钡餐造影及腹部CT扫描均显示十二指肠第三部(D3)存在梗阻迹象。手术探查发现D3和D4增厚导致管腔梗阻。行狭窄段切除并十二指肠空肠端侧吻合术。病变部位活检结果为结核。给予患者抗结核治疗6个月,随访(术后1年)情况良好。十二指肠结核是肠结核最罕见的形式,诊断极具难度。高度的怀疑指数,辅以放射学检查、剖腹探查及组织病理检查,才能明确诊断这一罕见病症。治疗方法包括手术治疗(针对梗阻性病变进行切除或旁路手术)和药物治疗(包括抗结核治疗)。

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1
Duodenal tuberculosis--a rare case report and review of literature.十二指肠结核——一例罕见病例报告及文献综述
Pol Przegl Chir. 2013 Aug;85(8):464-6. doi: 10.2478/pjs.2013.85.8.464.
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[Duodenal obstruction and upper gastrointestinal bleeding as the initial presentation of an isolated duodenal tuberculosis].[十二指肠梗阻和上消化道出血作为孤立性十二指肠结核的首发表现]
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Primary duodenal tuberculosis diagnosed by endoscopic biopsy.经内镜活检确诊的原发性十二指肠结核
Trop Gastroenterol. 1997 Apr-Jun;18(2):74-5.
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Tuberculosis of the duodenum.十二指肠结核
Am J Gastroenterol. 1979 Jul;72(1):36-40.
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Duodenal tuberculosis as seen by duodenoscopy.十二指肠镜检查所见的十二指肠结核
Am J Gastroenterol. 1976 Nov;66(5):483-6.
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Primary duodenal tuberculosis presenting as gastric-outlet obstruction: Its diagnosis.以胃出口梗阻为表现的原发性十二指肠结核:其诊断
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Gastric outlet obstruction: an unusual case of primary duodenal tuberculosis.胃出口梗阻:一例罕见的原发性十二指肠结核病例。
BMJ Case Rep. 2017 Mar 24;2017:bcr2016217966. doi: 10.1136/bcr-2016-217966.
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[Duodenal tuberculosis associated with lymph node tuberculosis (apropos of a surgical case)].[十二指肠结核合并淋巴结结核(附1例手术病例报告)]
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[Tuberculous stenosis of the duodenum].[十二指肠结核性狭窄]
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引用本文的文献

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Foregut tuberculosis: Too close but miles apart.前肠结核:看似相近实则相差甚远。
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Rare case of duodenal tuberculosis causing gastric outlet obstruction, a case report.十二指肠结核致胃出口梗阻罕见病例报告
Int J Surg Case Rep. 2023 Apr;105:108080. doi: 10.1016/j.ijscr.2023.108080. Epub 2023 Mar 28.
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Primary duodenal tuberculosis complicated with perforation: A review of literature and case report.原发性十二指肠结核合并穿孔:文献综述与病例报告
Ann Med Surg (Lond). 2021 May 12;66:102392. doi: 10.1016/j.amsu.2021.102392. eCollection 2021 Jun.
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Extrapulmonary tuberculosis: are statistical reports accurate?肺外结核病:统计报告准确吗?
Ther Adv Infect Dis. 2014 Apr;2(2):61-70. doi: 10.1177/2049936114528173.